IL-27 paves different roads to Tr1. (Q44757622)

6 December 2017

title

IL-27 paves different roads to Tr1. (English)

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6 December 2017

2

Axel Kallies

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6 December 2017

author name string

Ajithkumar Vasanthakumar

series ordinal

1

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6 December 2017

language of work or name

English

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publication date

1 April 2013

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European Journal of Immunology

6 December 2017

published in

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6 December 2017

volume

43

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6 December 2017

issue

4

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6 December 2017

page(s)

882-885

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Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

6 December 2017

cites work

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Interleukin-12 and the regulation of innate resistance and adaptive immunity

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IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

21 January 2018

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WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

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The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection

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Interleukin-27: balancing protective and pathological immunity

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Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

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A role for IL-27 in early regulation of Th1 differentiation

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WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production

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IL-27 limits IL-2 production during Th1 differentiation.

21 January 2018

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Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

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IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells

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A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.

21 January 2018

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Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells

21 January 2018

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c-Maf regulates IL-10 expression during Th17 polarization

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The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

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The regulation of IL-10 production by immune cells

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NFIL3/E4BP4 controls type 2 T helper cell cytokine expression

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IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines.

21 January 2018

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The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

21 January 2018

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CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2

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IL-21 mediates suppressive effects via its induction of IL-10.

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The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines

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BATF-JUN is critical for IRF4-mediated transcription in T cells

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CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs

21 January 2018

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B lymphocyte-induced maturation protein-1 contributes to intestinal mucosa homeostasis by limiting the number of IL-17-producing CD4+ T cells.

21 January 2018

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

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Fate mapping of IL-17-producing T cells in inflammatory responses

21 January 2018

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Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

21 January 2018

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Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+T cells

21 January 2018

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IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation

21 January 2018

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7 January 2021

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

1 reference

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7 January 2021

Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343479

7 January 2021

Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201343479

7 January 2021

Identifiers

DOI

10.1002/EJI.201343479

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6 December 2017

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