T cell-independent somatic hypermutation in murine B cells with an immature phenotype (Q44771096)

6 December 2017

T cell-independent somatic hypermutation in murine B cells with an immature phenotype (English)

1 reference

somatic hypermutation of immunoglobulin genes

6 December 2017

1 reference

Gene Ontology release 2020-05-02

1 reference

Changchuin Mao

1

1 reference

6 December 2017

Liying Jiang

2

1 reference

6 December 2017

Milena Melo-Jorge

3

1 reference

6 December 2017

Maya Puthenveetil

4

1 reference

6 December 2017

Xiuli Zhang

5

1 reference

6 December 2017

Michael C Carroll

6

1 reference

6 December 2017

Thereza Imanishi-Kari

7

1 reference

6 December 2017

language of work or name

English

0 references

publication date

1 February 2004

1 reference

6 December 2017

1 reference

6 December 2017

20

1 reference

6 December 2017

2

1 reference

6 December 2017

133-144

1 reference

Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation

6 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Somatic diversification of immunoglobulin heavy chain VDJ genes: evidence for somatic gene conversion in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Mutation drift and repertoire shift in the maturation of the immune response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Cutting edge: DNA polymerases mu and lambda are dispensable for Ig gene hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Organization of four mouse lambda light chain immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Heavy chain variable region. Multiple gene segments encode anti-4-(hydroxy-3-nitro-phenyl)acetyl idiotypic antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

The VH and CH immunoglobulin genes of swine: implications for repertoire development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

A quasi-monoclonal mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Mismatch repair co-opted by hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

B cell development in mice that lack one or both immunoglobulin kappa light chain genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Specific requirement for CD3epsilon in T cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

A new V gene expressed in lambda-2 light chains of the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Analysis of the targeting of the hypermutational machinery and the impact of subsequent selection on the distribution of nucleotide changes in human VHDJH rearrangements

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Perturbations in the impact of mutational activity on Vlambda genes in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Receptor editing: an approach by autoreactive B cells to escape tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

IL-7 administration alters the CD4:CD8 ratio, increases T cell numbers, and increases T cell function in the absence of activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Analysis of somatic hypermutation in mouse Peyer's patches using immunoglobulin kappa light-chain transgenes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Down-regulation of RAG1 and RAG2 gene expression in PreB cells after functional immunoglobulin heavy chain rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Patterns of nucleotide substitution in pseudogenes and functional genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

B cell development pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

The germinal center reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Lifetime of plasma cells in the bone marrow.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Both DNA strands of antibody genes are hypermutation targets

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

RAG2:GFP Knockin Mice Reveal Novel Aspects of RAG2 Expression in Primary and Peripheral Lymphoid Tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

The role of CD40-CD40 ligand (CD154) interactions in immunoglobulin light chain repertoire generation and somatic mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Somatic mutation in constant regions of mouse lambda 1 light chains

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

The Targeting of Somatic Hypermutation Closely Resembles That of Meiotic Mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

A critical role for complement in maintenance of self-tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

A hyperconversion mechanism generates the chicken light chain preimmune repertoire.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Evolution of Ig DNA sequence to target specific base positions within codons for somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Humoral immunity due to long-lived plasma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Receptor editing in self-reactive bone marrow B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Variability in the Lambda Light Chain Sequences of Mouse Antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Rabbit IgH sequences in appendix germinal centers: VH diversification by gene conversion-like and hypermutation mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappa

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900019-6

7 January 2021

10.1016/S1074-7613(04)00019-6

Identifiers

DOI

1 reference

6 December 2017

1 reference