Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution (Q45005831)

8 December 2017

Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution (English)

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8 December 2017

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8 December 2017

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Colin L Masters

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Giuseppe Donato Ciccotosto

8 December 2017

series ordinal

1

object named as

Giuseppe D Ciccotosto

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8 December 2017

10

Kevin J Barnham

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8 December 2017

5

Darryl Carrington

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8 December 2017

2

Deborah Tew

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8 December 2017

Danielle Smith

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8 December 2017

Robert A Cherny

series ordinal

8

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8 December 2017

language of work or name

English

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publication date

28 July 2004

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Journal of Biological Chemistry

8 December 2017

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8 December 2017

279

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8 December 2017

41

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8 December 2017

42528-42534

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Amyloid, the presenilins and Alzheimer's disease

8 December 2017

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https://api.crossref.org/works/10.1074%2FJBC.M406465200

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Neuroprotective approaches in experimental models of beta-amyloid neurotoxicity: relevance to Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Membrane-disordering effects of beta-amyloid peptides

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406465200

Disturbances of the neuronal calcium homeostasis in the aging nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Mechanisms of amyloid beta protein-induced modification in ion transport systems: implications for neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Theoretical models of the ion channel structure of amyloid beta-protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

beta-Amyloid protein amplifies calcium signalling in central neurons from the adult mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406465200

Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

A molecular switch in amyloid assembly: Met35 and amyloid beta-protein oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Methionine 35 oxidation reduces fibril assembly of the amyloid abeta-(1-42) peptide of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Spin probe clustering in human erythrocyte ghosts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

The interactions of the N-terminal fusogenic peptide of HIV-1 gp41 with neutral phospholipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

EPR Studies of the Motional Characteristics of the Phospholipid in Functional Reconstituted Sarcoplasmic Reticulum Membrane Vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Influence of lipid headgroup on the specificity and exchange dynamics in lipid-protein interactions. A spin-label study of myelin proteolipid apoprotein-phospholipid complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Increased viability of PC12 cells exposed to amyloid-beta peptide by transduction with human TAT-methionine sulfoxide reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Self-assembly of Abeta(1-42) into globular neurotoxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M406465200

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Membrane cholesterol interferes with neuronal apoptosis induced by soluble oligomers but not fibrils of amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

Alzheimer's disease: the cholesterol connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406465200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406465200

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8 December 2017

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