mTORC1 promotes denervation-induced muscle atrophy through a mechanism involving the activation of FoxO and E3 ubiquitin ligases (Q45084079)

9 December 2017

title

mTORC1 promotes denervation-induced muscle atrophy through a mechanism involving the activation of FoxO and E3 ubiquitin ligases (English)

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9 December 2017

10

Ronald A DePinho

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9 December 2017

Huibin Tang

1

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9 December 2017

Ken Inoki

2

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9 December 2017

Myung Lee

3

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9 December 2017

Erika Wright

4

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9 December 2017

Andy Khuong

5

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9 December 2017

Amanda Khuong

6

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9 December 2017

Sista Sugiarto

7

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9 December 2017

Matthew Garner

8

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9 December 2017

Jihye Paik

9

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9 December 2017

Daniel Goldman

11

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9 December 2017

Kun-Liang Guan

12

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9 December 2017

Joseph B Shrager

13

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9 December 2017

language of work or name

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25 February 2014

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9 December 2017

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9 December 2017

volume

7

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9 December 2017

issue

314

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9 December 2017

page(s)

ra18

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Motor neuron disease: systematic reviews of treatment for ALS and SMA.

9 December 2017

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Identification of ubiquitin ligases required for skeletal muscle atrophy

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Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

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Myogenin regulates denervation-dependent muscle atrophy in mouse soleus muscle

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Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

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mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

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Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

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S6 kinase deletion suppresses muscle growth adaptations to nutrient availability by activating AMP kinase

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.

21 January 2018

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Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy

21 January 2018

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mTOR pathway as a target in tissue hypertrophy.

21 January 2018

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21 January 2018

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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling

21 January 2018

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Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

21 January 2018

1 reference

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Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures

21 January 2018

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FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

21 January 2018

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S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover

21 January 2018

1 reference

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10.1126/SCISIGNAL.2004809

21 January 2018

Identifiers

DOI

1 reference

9 December 2017

1 reference