Caenorhabditis elegans PIAK, a phospholipid-independent kinase that activates the AKT/PKB survival kinase (Q45166166)

10 December 2017

title

Caenorhabditis elegans PIAK, a phospholipid-independent kinase that activates the AKT/PKB survival kinase (English)

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10 December 2017

main subject

Caenorhabditis elegans

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author name string

Li Y

series ordinal

1

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10 December 2017

Dowbenko D

series ordinal

2

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10 December 2017

Lasky LA

series ordinal

3

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10 December 2017

language of work or name

English

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publication date

23 March 2001

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Journal of Biological Chemistry

10 December 2017

published in

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10 December 2017

volume

276

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10 December 2017

issue

23

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10 December 2017

page(s)

20323-20329

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Signalling through the lipid products of phosphoinositide-3-OH kinase

10 December 2017

cites work

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PI3K: downstream AKTion blocks apoptosis

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

21 January 2018

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

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Role of translocation in the activation and function of protein kinase B

21 January 2018

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

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PDK1, one of the missing links in insulin signal transduction?

21 January 2018

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

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Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

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The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

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Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 January 2018

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A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

21 January 2018

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Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

21 January 2018

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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

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A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

21 January 2018

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Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase

21 January 2018

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The dynamics of protein kinase B regulation during B cell antigen receptor engagement

21 January 2018

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Inhibition of cyclin-dependent kinases by purine analogues

21 January 2018

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Modulation of Akt kinase activity by binding to Hsp90

21 January 2018

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Protein kinase C is required for light adaptation in Drosophila photoreceptors

21 January 2018

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High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

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Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

21 January 2018

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cAMP stimulates protein kinase B in a Wortmannin-insensitive manner

21 January 2018

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G1 phase arrest by the phosphatidylinositol 3-kinase inhibitor LY 294002 is correlated to up-regulation of p27Kip1 and inhibition of G1 CDKs in choroidal melanoma cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M101309200

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10 December 2017

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