Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. (Q45259224)

11 December 2017

Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. (English)

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11 December 2017

6

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11 December 2017

Morag C Martin

1

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11 December 2017

Lindsey A Allan

2

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11 December 2017

Michelle Lickrish

3

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11 December 2017

Catherine Sampson

4

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11 December 2017

Nick Morrice

5

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11 December 2017

language of work or name

English

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publication date

9 February 2005

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Journal of Biological Chemistry

11 December 2017

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11 December 2017

280

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11 December 2017

15

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11 December 2017

15449-15455

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Programmed cell death in animal development

11 December 2017

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Intrinsic tumour suppression

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The protein structures that shape caspase activity, specificity, activation and inhibition

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

21 January 2018

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

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Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

21 January 2018

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Structure and function of cyclic nucleotide-dependent protein kinases

21 January 2018

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PKA: a portrait of protein kinase dynamics

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

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The pro-apoptotic protein Bim is a convergence point for cAMP/protein kinase A- and glucocorticoid-promoted apoptosis of lymphoid cells

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Activation of cAMP signaling transiently inhibits apoptosis in vascular smooth muscle cells in a site upstream of caspase-3.

21 January 2018

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The glucagon-like peptide-2 receptor mediates direct inhibition of cellular apoptosis via a cAMP-dependent protein kinase-independent pathway

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Attenuation of macrophage apoptosis by the cAMP-signaling system

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cAMP protection of pancreatic cancer cells against apoptosis induced by ERK inhibition.

21 January 2018

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Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway.

21 January 2018

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Cyclic AMP promotes cAMP-responsive element-binding protein-dependent induction of cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK.

21 January 2018

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cAMP Dose-dependently prevents palmitate-induced apoptosis by both protein kinase A- and cAMP-guanine nucleotide exchange factor-dependent pathways in beta-cells

21 January 2018

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Cell death: critical control points

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X-linked IAP is a direct inhibitor of cell-death proteases

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Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology

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Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

21 January 2018

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Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

21 January 2018

1 reference

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

21 January 2018

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Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes

21 January 2018

1 reference

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Oligomerization and activation of caspase-9, induced by Apaf-1 CARD.

21 January 2018

1 reference

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WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

21 January 2018

1 reference

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Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

21 January 2018

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BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival

21 January 2018

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Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

21 January 2018

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Phosphorylation of the pro-apoptotic protein BAD on serine 155, a novel site, contributes to cell survival

21 January 2018

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Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

21 January 2018

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Bad-deficient mice develop diffuse large B cell lymphoma

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G2 arrest in Xenopus oocytes depends on phosphorylation of cdc25 by protein kinase A.

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Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M414325200

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11 December 2017

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