Raf-1 without MEK? (Q45345638)

13 December 2017

Raf-1 without MEK? (English)

1 reference

13 December 2017

M S Murakami

1

1 reference

PubMed ID

11579234

13 December 2017

D K Morrison

series ordinal

2

1 reference

13 December 2017

11 September 2001

1 reference

Science's STKE : signal transduction knowledge environment

13 December 2017

1 reference

13 December 2017

2001

1 reference

13 December 2017

99

1 reference

13 December 2017

pe30

1 reference

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

13 December 2017

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

MEK kinase activity is not necessary for Raf-1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Isotype-specific functions of Raf kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Autoregulation of the Raf-1 serine/threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

The complexity of Raf-1 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Senescence of human fibroblasts induced by oncogenic Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Ras signalling and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Apoptosis: Ras to the rescue in the fly eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Endothelial apoptosis in Braf-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Craf-1 protein kinase is essential for mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Inhibition of the Raf-1 kinase by cyclic AMP agonists causes apoptosis of v-abl-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Protective role of Raf-1 in Salmonella-induced macrophage apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Ras promotes cell survival in Drosophila by downregulating hid expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Oncogenic K-Ras and basic fibroblast growth factor prevent Fas-mediated apoptosis in fibroblasts through activation of mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Activation of (His)6-Raf-1 in vitro by partially purified plasma membranes from v-Ras-transformed and serum-stimulated fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Raf revealed in life-or-death decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2001.99.PE30

10.1126/STKE.2001.99.PE30

21 January 2018

Identifiers

DOI

1 reference

13 December 2017

1 reference

PubMed ID

11579234