Engineered herpes simplex virus expressing bacterial cytosine deaminase for experimental therapy of brain tumors (Q45411954)

14 December 2017

title

Engineered herpes simplex virus expressing bacterial cytosine deaminase for experimental therapy of brain tumors (English)

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14 December 2017

M B Guffey

1

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14 December 2017

J N Parker

2

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14 December 2017

W S Luckett

3

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14 December 2017

G Y Gillespie

4

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14 December 2017

S Meleth

5

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14 December 2017

R J Whitley

6

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14 December 2017

J M Markert

7

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14 December 2017

publication date

22 September 2006

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14 December 2017

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14 December 2017

volume

14

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14 December 2017

issue

1

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14 December 2017

page(s)

45-56

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

14 December 2017

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Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins

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Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumors

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Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

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A generalized technique for deletion of specific genes in large genomes: alpha gene 22 of herpes simplex virus 1 is not essential for growth.

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Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

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Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model

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The V domain of herpesvirus Ig-like receptor (HIgR) contains a major functional region in herpes simplex virus-1 entry into cells and interacts physically with the viral glycoprotein D

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Cytotoxicity of adenoviral-mediated cytosine deaminase plus 5-fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model

21 January 2018

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Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes

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Interleukin 12 secretion enhances antitumor efficacy of oncolytic herpes simplex viral therapy for colorectal cancer

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7 January 2021

Naked DNA gene delivery to the liver

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7 January 2021

The ectodomain of a novel member of the immunoglobulin subfamily related to the poliovirus receptor has the attributes of a bona fide receptor for herpes simplex virus types 1 and 2 in human cells

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700978

7 January 2021

Pyrimidine, purine and nitrogen control of cytosine deaminase synthesis in Escherichia coli K 12. Involvement of the glnLG and purR genes in the regulation of codA expression

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700978

7 January 2021

Neuroblastoma grafts are noninvasively removed within mouse neocortex by selective laser activation of intracellular photolytic chromophore

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https://api.crossref.org/works/10.1038%2FSJ.CGT.7700978

7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700978

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Dimensions Publication ID

14 December 2017

1027501180

0 references

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