Simian immunodeficiency virus envelope compartmentalizes in brain regions independent of neuropathology (Q45415196)

14 December 2017

Simian immunodeficiency virus envelope compartmentalizes in brain regions independent of neuropathology (English)

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Simian immunodeficiency virus

14 December 2017

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Samantha S Soldan

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Francisco González-Scarano

14 December 2017

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object named as

Francisco González-Scarano

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Maria F Chen

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Susan Westmoreland

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Elena V Ryzhova

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Julio Martín-García

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Andrew Lackner

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1 April 2006

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14 December 2017

Journal of NeuroVirology

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12

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73-89

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https://scigraph.springernature.com/pub.10.1080/13550280600654565

14 December 2017

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Evolution of envelope sequences from the genital tract and peripheral blood of women infected with clade A human immunodeficiency virus type 1.

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The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex

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Role of microglial cells in selective replication of simian immunodeficiency virus genotypes in the brain

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Independent evolution of human immunodeficiency virus (HIV) drug resistance mutations in diverse areas of the brain in HIV-infected patients, with and without dementia, on antiretroviral treatment

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The detection of disease clustering and a generalized regression approach

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Parallel evolution of drug resistance in HIV: failure of nonsynonymous/synonymous substitution rate ratio to detect selection

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Antigenic variation of SIV: mutations in V4 alter the neutralization profile

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Simian immunodeficiency virus: a model for neuroAIDS.

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Variation in simian immunodeficiency virus env is confined to V1 and V4 during progression to simian AIDS.

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The neuropathogenesis of HIV-1 infection

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Identification of shared populations of human immunodeficiency virus type 1 infecting microglia and tissue macrophages outside the central nervous system.

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Rapid progression to simian AIDS can be accompanied by selection of CD4-independent gp120 variants with impaired ability to bind CD4.

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Coreceptor specificity of temporal variants of simian immunodeficiency virus Mne.

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Detecting isolation by distance using phylogenies of genes

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Differential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate

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Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enh

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12 December 2020

CD4-independent infection of HIV and SIV: implications for envelope conformation and cell tropism in vivo

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Analysis of human immunodeficiency virus type 1 gp160 sequences from a patient with HIV dementia: evidence for monocyte trafficking into brain

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Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

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Low levels of human immunodeficiency virus replication in the brain tissue of children with severe acquired immunodeficiency syndrome encephalopathy

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Human immunodeficiency virus-associated dementia

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Simian immunodeficiency virus encephalitis: analysis of envelope sequences from individual brain multinucleated giant cells and tissue samples

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In search of molecular darwinism

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Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population

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Phylodynamic analysis of human immunodeficiency virus type 1 in distinct brain compartments provides a model for the neuropathogenesis of AIDS.

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Microglia-passaged simian immunodeficiency virus induces neurophysiological abnormalities in monkeys

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Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques

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Evolution of coreceptor use and CD4-independence in envelope clones derived from SIVsm-infected macaques

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Independent evolution of HIV type 1 in different brain regions.

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Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants

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Viral genetic evolution in macaques infected with molecularly cloned simian immunodeficiency virus correlates with the extent of persistent viremia

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Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences

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HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

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Analysis of envelope changes acquired by SIVmac239 during neuroadaption in rhesus macaques

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CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

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Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants.

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Pathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulence

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Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophages and microglia by T helper type 2 cytokines

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Influence of random genetic drift on human immunodeficiency virus type 1 env evolution during chronic infection

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Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protein of brain-derived sequences

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12 December 2020

Pathogenesis of SIV encephalitis. Selection and replication of neurovirulent SIV

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HIV-associated neurologic disease incidence changes:: Multicenter AIDS Cohort Study, 1990-1998

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Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

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HIV-associated cognitive impairment before and after the advent of combination therapy

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12 December 2020

Localization of simian immunodeficiency virus in the central nervous system of rhesus monkeys

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Determinants within gp120 and gp41 contribute to CD4 independence of SIV Envs

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12 December 2020

MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment

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Genetic drift and within-host metapopulation dynamics of HIV-1 infection

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A Cell-Cell Fusion Assay to Monitor HIV-1 Env Interactions with Chemokine Receptors

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Unique Pattern of Convergent Envelope Evolution in Simian Immunodeficiency Virus-Infected Rapid Progressor Macaques: Association with CD4-Independent Usage of CCR5

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CSF antiretroviral drug penetrance and the treatment of HIV-associated psychomotor slowing

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Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS.

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Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection

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Compartmentalization of human immunodeficiency virus type 1 between blood monocytes and CD4+ T cells during infection

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Analysis of simian immunodeficiency virus sequence variation in tissues of rhesus macaques with simian AIDS

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Structure of an unliganded simian immunodeficiency virus gp120 core

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Identification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins

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Compartmentalization of surface envelope glycoprotein of human immunodeficiency virus type 1 during acute and chronic infection

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The central nervous system as a reservoir for simian immunodeficiency virus (SIV): steady-state levels of SIV DNA in brain from acute through asymptomatic infection

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12 December 2020

10.1080/13550280600654565

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14 December 2017

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