Patient-derived xenografts undergo mouse-specific tumor evolution. (Q46291099)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28991255%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Patient-derived xenografts undergo mouse-specific tumor evolution (English)

1 reference

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1 April 2020

1 reference

1 reference

2

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1 April 2020

Jesse S Boehm

9

1 reference

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1 April 2020

Noah F Greenwald

4

1 reference

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1 April 2020

Coyin Oh

5

1 reference

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1 April 2020

Juliann Shih

6

1 reference

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1 April 2020

Todd Golub

11

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1 April 2020

10

Rameen Beroukhim

1 reference

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1 April 2020

author name string

Uri Ben-David

1

1 reference

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1 April 2020

Yuen-Yi Tseng

3

1 reference

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1 April 2020

James M McFarland

7

1 reference

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1 April 2020

Bang Wong

8

1 reference

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1 April 2020

language of work or name

English

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publication date

9 October 2017

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1 April 2020

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1 April 2020

volume

49

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1 April 2020

page(s)

1567-1575

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1 April 2020

issue

11

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describes a project that uses

1 April 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5659952

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ng.3967

0 references

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High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

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Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

10 July 2018

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Genome-wide mutation profiles of colorectal tumors and associated liver metastases at the exome and transcriptome levels

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SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

10 July 2018

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Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development

10 July 2018

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Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies

10 July 2018

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Subclonal Genomic Architectures of Primary and Metastatic Colorectal Cancer Based on Intratumoral Genetic Heterogeneity

10 July 2018

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Moment based gene set tests

10 July 2018

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Targeting the adaptability of heterogeneous aneuploids

10 July 2018

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Intra-tumor genetic heterogeneity and mortality in head and neck cancer: analysis of data from the Cancer Genome Atlas

10 July 2018

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limma powers differential expression analyses for RNA-sequencing and microarray studies

10 July 2018

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Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.

10 July 2018

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Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells

10 July 2018

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Patient-derived xenograft models: an emerging platform for translational cancer research

10 July 2018

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Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigating molecular mechanisms of drug resistance

10 July 2018

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Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages--strategies for data mining in support of therapeutic studies

10 July 2018

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Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles

10 July 2018

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Comparative genomic analysis of primary and synchronous metastatic colorectal cancers

10 July 2018

1 reference

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High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development

10 July 2018

1 reference

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Phenotypic and transcriptional fidelity of patient-derived colon cancer xenografts in immune-deficient mice

10 July 2018

1 reference

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Chromosome missegregation rate predicts whether aneuploidy will promote or suppress tumors.

10 July 2018

1 reference

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Pan-cancer patterns of somatic copy number alteration

10 July 2018

1 reference

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Tumor grafts derived from patients with head and neck squamous carcinoma authentically maintain the molecular and histologic characteristics of human cancers

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models

10 July 2018

1 reference

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Patient-derived tumor xenografts: transforming clinical samples into mouse models

10 July 2018

1 reference

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The clinical relevance of cancer cell lines.

10 July 2018

1 reference

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Novel dedifferentiated liposarcoma xenograft models reveal PTEN down-regulation as a malignant signature and response to PI3K pathway inhibition

10 July 2018

1 reference

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Absolute quantification of somatic DNA alterations in human cancer

10 July 2018

1 reference

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Patient-derived tumour xenografts as models for oncology drug development

10 July 2018

1 reference

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737

10 July 2018

1 reference

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Renal cell carcinoma primary cultures maintain genomic and phenotypic profile of parental tumor tissues

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Paradoxical relationship between chromosomal instability and survival outcome in cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Targeting chromosomal instability and tumour heterogeneity in HER2-positive breast cancer

10 July 2018

1 reference

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Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

10 July 2018

1 reference

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Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

10 July 2018

1 reference

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A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro

10 July 2018

1 reference

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Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts

10 July 2018

1 reference

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An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

10 July 2018

1 reference

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Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Karyotypic complexity of the NCI-60 drug-screening panel.

10 July 2018

1 reference

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Molecular Evolution Patterns in Metastatic Lymph Nodes Reflect the Differential Treatment Response of Advanced Primary Lung Cancer.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Gene expression analysis identifies global gene dosage sensitivity in cancer.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target.

15 August 2018

1 reference

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Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

15 August 2018

1 reference

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A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5659952

Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations

15 August 2018

1 reference

7 January 2021

Virtual karyotyping of pluripotent stem cells on the basis of their global gene expression profiles

1 reference

7 January 2021

Genetic landscape of metastatic and recurrent head and neck squamous cell carcinoma

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7 January 2021

Sperm aneuploidy frequencies analysed before and after chemotherapy in testicular cancer and Hodgkin's lymphoma patients

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7 January 2021

Identifiers

DOI

10.1038/NG.3967

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28991255%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28991255%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference