Sphingosine 1-phosphate receptor agonism impairs skin dendritic cell migration and homing to secondary lymphoid tissue: association with prolonged allograft survival (Q46434977)

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scientific article published on 9 August 2008

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English	Sphingosine 1-phosphate receptor agonism impairs skin dendritic cell migration and homing to secondary lymphoid tissue: association with prolonged allograft survival	scientific article published on 9 August 2008

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

Sphingosine 1-phosphate receptor agonism impairs skin dendritic cell migration and homing to secondary lymphoid tissue: association with prolonged allograft survival (English)

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

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based on heuristic

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Angus W. Thomson

7

object named as

Angus W Thomson

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

author name string

Yuk Yuen Lan

1

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22 December 2017

http://europepmc.org/abstract/MED/18694829

Daisuke Tokita

2

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22 December 2017

http://europepmc.org/abstract/MED/18694829

Zhiliang Wang

3

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

Hao Chen Wang

4

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

Jianghua Zhan

5

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

Volker Brinkmann

6

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22 December 2017

http://europepmc.org/abstract/MED/18694829

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publication date

9 August 2008

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Europe PubMed Central

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22 December 2017

http://europepmc.org/abstract/MED/18694829

Transplant Immunology

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22 December 2017

http://europepmc.org/abstract/MED/18694829

20

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PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

1-2

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

88-94

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

Sphingosine 1-phosphate receptor modulators: a new class of immunosuppressants.

1 reference

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The immune modulator FTY720 targets sphingosine 1-phosphate receptors

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Synthesis and immunosuppressive activity of 2-substituted 2-aminopropane-1,3-diols and 2-aminoethanols

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FTY720: from bench to bedside

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FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory.

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Novel insights into the mechanism of action of FTY720 in a transgenic model of allograft rejection: implications for therapy of chronic rejection.

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Pharmacodynamics of single doses of the novel immunosuppressant FTY720 in stable renal transplant patients.

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Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

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Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD.

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FTY720, a novel immunomodulator: efficacy and safety results from the first phase 2A study in de novo renal transplantation

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Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology

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Egress: a receptor-regulated step in lymphocyte trafficking

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Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

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Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation

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Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

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Sphingosine-1-phosphate: an enigmatic signalling lipid

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Generation and metabolism of bioactive sphingosine-1-phosphate

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FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function.

1 reference

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7 January 2021

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

1 reference

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Dendritic cells and the control of immunity

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The dendritic cell system and its role in immunogenicity

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Dendritic cells, tolerance induction and transplant outcome

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Tolerogenic dendritic cells

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Tolerogenic dendritic cells and the quest for transplant tolerance

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Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses

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The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells.

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The sphingosine-1-phosphate receptor agonist FTY720 modulates dendritic cell trafficking in vivo

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Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function

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Langerhans cells - dendritic cells of the epidermis.

1 reference

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A close-up view of migrating Langerhans cells in the skin.

1 reference

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Immature and mature CD8alpha+ dendritic cells prolong the survival of vascularized heart allografts

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Cytokine production by mouse myeloid dendritic cells in relation to differentiation and terminal maturation induced by lipopolysaccharide or CD40 ligation

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Heart, but not skin, allografts from donors lacking Flt3 ligand exhibit markedly prolonged survival time

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Promotion of skin graft tolerance across MHC barriers by mobilization of dendritic cells in donor hemopoietic cell infusions

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Migration and maturation of Langerhans cells in skin transplants and explants

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Migration of CD4 T cells and dendritic cells toward sphingosine 1-phosphate (S1P) is mediated by different receptor subtypes: S1P regulates the functions of murine mature dendritic cells via S1P receptor type 3.

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Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection

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CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions

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Sphingosine-1-phosphate mediates migration of mature dendritic cells.

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Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

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The sphingosine 1-phosphate receptor agonist FTY720 differentially affects the sequestration of CD4+/CD25+ T-regulatory cells and enhances their functional activity

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Overlapping signaling pathways of sphingosine 1-phosphate and TGF-beta in the murine Langerhans cell line XS52.

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Requirement of Rac1 and Rac2 Expression by Mature Dendritic Cells for T Cell Priming

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Immunologic 'ignorance' of vascularized organ transplants in the absence of secondary lymphoid tissue

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FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments

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The leukotriene C(4) transporter MRP1 regulates CCL19 (MIP-3beta, ELC)-dependent mobilization of dendritic cells to lymph nodes

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A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels

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A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model

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Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor.

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Identifiers

10.1016/J.TRIM.2008.07.004

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/18694829

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