Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner. (Q46440221)

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10 January 2020

title

Tpl2/cot signals activate ERK, JNK, and NF-kappaB in a cell-type and stimulus-specific manner (English)

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10 January 2020

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Aristides G Eliopoulos

5

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10 January 2020

author name string

Santasabuj Das

1

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10 January 2020

Jeonghee Cho

2

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10 January 2020

Irina Lambertz

3

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10 January 2020

Michelle A Kelliher

4

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10 January 2020

Keyong Du

6

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10 January 2020

Philip N Tsichlis

7

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language of work or name

English

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publication date

15 April 2005

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Journal of Biological Chemistry

10 January 2020

published in

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10 January 2020

volume

280

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10 January 2020

issue

25

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10 January 2020

page(s)

23748-23757

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Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

10 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Multiple mitogen-activated protein kinase signaling pathways connect the cot oncoprotein to the c-jun promoter and to cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Tumor necrosis factor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

The essential role of MEKK3 in TNF-induced NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

The role of the death-domain kinase RIP in tumour-necrosis-factor-induced activation of mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Missing pieces in the NF-kappaB puzzle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Tumor necrosis factor alpha-induced phosphorylation of RelA/p65 on Ser529 is controlled by casein kinase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Activation of NF-kappaB by Toxoplasma gondii correlates with increased expression of antiapoptotic genes and localization of phosphorylated IkappaB to the parasitophorous vacuole membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

TNF-R1 signaling: a beautiful pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

IkappaB kinase is an essential component of the Tpl2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

The oncogenic protein kinase Tpl-2/Cot contributes to Epstein-Barr virus-encoded latent infection membrane protein 1-induced NF-kappaB signaling downstream of TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Fibroblast biology. Synovial fibroblasts in rheumatoid arthritis: leading role or chorus line?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

Anti-TNF-alpha therapies: the next generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412837200

21 January 2018

Identifiers

DOI

10.1074/JBC.M412837200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15833743%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference