Substrate recognition and ubiquitination of SCFSkp2/Cks1 ubiquitin-protein isopeptide ligase. (Q46463573)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

title

Substrate recognition and ubiquitination of SCFSkp2/Cks1 ubiquitin-protein isopeptide ligase (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

author name string

Shuichan Xu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Mahan Abbasian

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Palka Patel

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Kristen Jensen-Pergakes

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Christian R Lombardo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Brian E Cathers

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Weilin Xie

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Frank Mercurio

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

David Giegel

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

Sarah Cox

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

language of work or name

English

0 references

publication date

4 April 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

28 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

volume

282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

page(s)

15462-15470

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

28 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Protein destruction: adapting roles for Cks proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Therapeutic anti-cancer targets upstream of the proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Mechanisms underlying ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Structural basis of the Cks1-dependent recognition of p27(Kip1) by the SCF(Skp2) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Three different binding sites of Cks1 are required for p27-ubiquitin ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Noncatalytic requirement for cyclin A-cdk2 in p27 turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Fast-response proteomics by accelerated in-gel digestion of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Substrate specificity of CDK2-cyclin A. What is optimal?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

The structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent roles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

In vitro SCFbeta-Trcp1-mediated IkappaBalpha ubiquitination assay for high-throughput screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610758200

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

21 January 2018

2 references

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI0215795

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1172/JCI15795

Identifiers

DOI

10.1074/JBC.M610758200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17409098%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

1 reference