A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases (Q46523543)

22 December 2017

title

A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases (English)

1 reference

22 December 2017

genome-wide association study

main subject

1 reference

3

1 reference

22 December 2017

Antonio Lentini

Antonio Lentini

13

0 references

Daniel Eklund

Daniel Eklund

8

0 references

Ingrid Kockum

Ingrid Kockum

10

0 references

Sergio E Baranzini

4

Sergio Baranzini

1 reference

22 December 2017

Tomas Olsson

19

Tomas Olsson

1 reference

22 December 2017

author name string

Mika Gustafsson

1

1 reference

22 December 2017

Danuta R Gawel

2

1 reference

22 December 2017

Janne Björkander

5

1 reference

22 December 2017

Robert Blomgran

6

1 reference

22 December 2017

Sandra Hellberg

7

1 reference

22 December 2017

Jan Ernerudh

9

1 reference

22 December 2017

Aelita Konstantinell

11

1 reference

22 December 2017

Riita Lahesmaa

12

1 reference

22 December 2017

H Robert I Liljenström

14

1 reference

22 December 2017

Lina Mattson

15

1 reference

22 December 2017

Andreas Matussek

16

1 reference

22 December 2017

Johan Mellergård

17

1 reference

22 December 2017

Melissa Mendez

18

1 reference

22 December 2017

Miguel A Pujana

20

1 reference

22 December 2017

Omid Rasool

21

1 reference

22 December 2017

Jordi Serra-Musach

22

1 reference

22 December 2017

Margaretha Stenmarker

23

1 reference

22 December 2017

Subhash Tripathi

24

1 reference

22 December 2017

Miro Viitala

25

1 reference

22 December 2017

Hui Wang

26

1 reference

22 December 2017

Huan Zhang

27

1 reference

22 December 2017

Colm E Nestor

28

1 reference

22 December 2017

Mikael Benson

29

1 reference

22 December 2017

language of work or name

English

0 references

publication date

1 November 2015

1 reference

22 December 2017

Science Translational Medicine

published in

1 reference

22 December 2017

volume

7

1 reference

22 December 2017

issue

313

1 reference

22 December 2017

page(s)

313ra178

1 reference

22 December 2017

Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Integrated genomic and prospective clinical studies show the importance of modular pleiotropy for disease susceptibility, diagnosis and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

T-helper 2 immunity is associated with reduced risk of myocardial infarction and stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

The central role of CD4(+) T cells in the antitumor immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Profiling of human CD4+ T-cell subsets identifies the TH2-specific noncoding RNA GATA3-AS1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

AnimalTFDB: a comprehensive animal transcription factor database

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Integrating multiple evidence sources to predict transcription factor binding in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Molecular profiling of CD3-CD4+ T cells from patients with the lymphocytic variant of hypereosinophilic syndrome reveals targeting of growth control pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

DNA methylation changes separate allergic patients from healthy controls and may reflect altered CD4+ T-cell population structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

CD247 variants and single-nucleotide polymorphisms observed in systemic lupus erythematosus patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Targeted omics and systems medicine: personalising care.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Highly interconnected genes in disease-specific networks are enriched for disease-associated polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

BEDTools: a flexible suite of utilities for comparing genomic features

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

maSigPro: a method to identify significantly differential expression profiles in time-course microarray experiments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Fewer permutations, more accurate P-values

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Fast gapped-read alignment with Bowtie 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Model-based analysis of ChIP-Seq (MACS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

GWASdb: a database for human genetic variants identified by genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

The Inferelator: an algorithm for learning parsimonious regulatory networks from systems-biology data sets de novo

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Constructing and analyzing a large-scale gene-to-gene regulatory network--lasso-constrained inference and biological validation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Reverse engineering of gene networks with LASSO and nonlinear basis functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Robust data-driven incorporation of prior knowledge into the inference of dynamic regulatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Functional association networks as priors for gene regulatory network inference

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Network modeling of the transcriptional effects of copy number aberrations in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

rSNPBase: a database for curated regulatory SNPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAD2722

10.1126/SCITRANSLMED.AAD2722

21 January 2018

Identifiers

DOI

1 reference

22 December 2017

1 reference

22 December 2017