Functional characterization of the CgPGS1 gene reveals a link between mitochondrial phospholipid homeostasis and drug resistance in Candida glabrata (Q46699248)

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English	Functional characterization of the CgPGS1 gene reveals a link between mitochondrial phospholipid homeostasis and drug resistance in Candida glabrata	scientific article

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scholarly article

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

Functional characterization of the CgPGS1 gene reveals a link between mitochondrial phospholipid homeostasis and drug resistance in Candida glabrata (English)

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

Candida glabrata

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author name string

Monika Batova

1

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

Silvia Borecka-Melkusova

2

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

Maria Simockova

3

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

Vladimira Dzugasova

4

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

Eduard Goffa

5

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

Julius Subik

6

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

publication date

15 March 2008

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

Current Genetics

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

53

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

5

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

313-322

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

https://scigraph.springernature.com/pub.10.1007/s00294-008-0187-9

0 references

Cloning of the Bacillus firmus OF4 cls gene and characterization of its gene product.

1 reference

https://api.crossref.org/works/10.1007%2FS00294-008-0187-9

21 January 2018

New insights into the regulation of cardiolipin biosynthesis in yeast: implications for Barth syndrome.

1 reference

https://api.crossref.org/works/10.1007%2FS00294-008-0187-9

21 January 2018

Phosphatidylglycerophosphate synthase from yeast

1 reference

https://api.crossref.org/works/10.1007%2FS00294-008-0187-9

21 January 2018

Phospholipid and sterol analysis of plasma membranes of azole-resistant Candida albicans strains.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiolipin prevents rate-dependent uncoupling and provides osmotic stability in yeast mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interorganellar communication. Altered nuclear gene expression profiles in a yeast mitochondrial dna mutant.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-linked cardioskeletal myopathy and neutropenia (Barth syndrome): respiratory-chain abnormalities in cultured fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence and inactivation of the pss gene of Escherichia coli. Phosphatidylethanolamine may not be essential for cell viability

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nuclear mutant ofS. cerevisiaenon-tolerating the cytoplasmic petite mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

YDL142c encodes cardiolipin synthase (Cls1p) and is non-essential for aerobic growth of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthesis and functional role of cardiolipin

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple signals from dysfunctional mitochondria activate the pleiotropic drug resistance pathway in Saccharomyces cerevisiae.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient homologous and illegitimate recombination in the opportunistic yeast pathogen Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maintenance and integrity of the mitochondrial genome: a plethora of nuclear genes in the budding yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pel1 mutant of Saccharomyces cerevisiae is deficient in cardiolipin and does not survive the disruption of the CHO1 gene encoding phosphatidylserine synthase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic lethal interaction between the pel1 and op1 mutations in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of the pathogenic yeast Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tightly associated cardiolipin in the bovine heart mitochondrial ATP synthase as analyzed by 31P nuclear magnetic resonance spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrograde regulation of multidrug resistance in Saccharomyces cerevisiae.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome evolution in yeasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid, efficient method for isolating DNA from yeast.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylglycerolphosphate synthase encoded by the PEL1/PGS1 gene in Saccharomyces cerevisiae is localized in mitochondria and its expression is regulated by phospholipid precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular characterization of the PEL1 gene encoding a putative phosphatidylserine synthase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PEL1 gene (renamed PGS1) encodes the phosphatidylglycero-phosphate synthase of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro studies of phospholipid biosynthesis in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of mitochondrial anionic phospholipids causes an inhibition of translation of protein components of the electron transport chain. A yeast genetic model system for the study of anionic phospholipid function in mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ergosterol depletion and 4-methyl sterols accumulation in the yeast Saccharomyces cerevisiae treated with an antifungal, 6-amino-2-n-pentylthiobenzothiazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Saccharomyces cerevisiae multidrug resistance gene expression inversely correlates with the status of the F(0) component of the mitochondrial ATPase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reconstituted ADP/ATP carrier activity has an absolute requirement for cardiolipin as shown in cysteine mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane fluidity affects functions of Cdr1p, a multidrug ABC transporter of Candida albicans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of fluconazole sensitivity by the interaction of mitochondria and erg3p in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PerlPrimer: cross-platform, graphical primer design for standard, bisulphite and real-time PCR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of the cell integrity pathway in saccharomyces cerevisiae suppresses temperature sensitivity of the pgs1Delta mutant.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of clinical and food Saccharomyces cerevisiae isolates on the basis of potential virulence factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bongkrekic acid sensitivity of respiration-deficient mutants and of petite-negative species of yeasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of the PEL1 gene of Saccharomyces cerevisiae that is essential for the viability of petite mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primer3 on the WWW for general users and for biologist programmers

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tn7-based genome-wide random insertional mutagenesis of Candida glabrata.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiolipin stabilizes respiratory chain supercomplexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of cardiolipin results in temperature sensitivity, respiratory defects, and mitochondrial DNA instability independent of pet56.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The KlPGS1 gene encoding phosphatidylglycerolphosphate synthase in Kluyveromyces lactis is essential and assigned to chromosome I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mucidin Resistance in Yeast. Isolation, Characterization and Genetic Analysis of Nuclear and Mitochondrial Mucidin-Resistant Mutants of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obligatory requirement of intramitochondrial ATP for normal functionning of the eucaryotic cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug susceptibilities of yeast cells are affected by membrane lipid composition

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiolipin requirement for electron transfer in complex I and III of the mitochondrial respiratory chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A yeast by any other name: Candida glabrata and its interaction with the host

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiolipin is not essential for the growth of Saccharomyces cerevisiae on fermentable or non-fermentable carbon sources

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of azole resistance in petite mutants of Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of function of KRE5 suppresses temperature sensitivity of mutants lacking mitochondrial anionic lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18343926

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00294-008-0187-9

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18343926

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