A new nerve growth factor-mimetic peptide active on neuropathic pain in rats (Q46704890)

http://europepmc.org/abstract/MED/18337399

24 December 2017

title

A new nerve growth factor-mimetic peptide active on neuropathic pain in rats (English)

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http://europepmc.org/abstract/MED/18337399

24 December 2017

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Michele Papa

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Lilia Alberghina

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Enzo Martegani

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Anna Maria Colangelo

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Carlo Cavaliere

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Laura Zaccaro

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author name string

Maria Rosaria Bianco

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Luigi Vitagliano

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Luca De Gioia

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Donatella Diana

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Daniele Colombo

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Cristina Redaelli

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Giancarlo Morelli

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Paolo Sarmientos

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language of work or name

English

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publication date

1 March 2008

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http://europepmc.org/abstract/MED/18337399

24 December 2017

published in

Journal of Neuroscience

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volume

28

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issue

11

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page(s)

2698-2709

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Effect of NGF and anti-NGF on neuropathic pain in rats following chronic constriction injury of the sciatic nerve

16 May 2020

cites work

1 reference

12 December 2020

Peripheral mononeuropathy induced by loose ligation of the sciatic nerve in the rat: behavioral, electrophysiological and histopathologic studies

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12 December 2020

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

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12 December 2020

A designed peptidomimetic agonistic ligand of TrkA nerve growth factor receptors.

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12 December 2020

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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12 December 2020

Genuine Monovalent Ligands of TrkA Nerve Growth Factor Receptors Reveal a Novel Pharmacological Mechanism of Action

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12 December 2020

Nerve growth factor (NGF) loop 4 dimeric mimetics activate ERK and AKT and promote NGF-like neurotrophic effects

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12 December 2020

The involvement of glial cells in the development of morphine tolerance

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12 December 2020

Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA

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12 December 2020

Molecular kinetics of nerve growth factor receptor trafficking and activation

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12 December 2020

Nerve growth factor for the treatment of diabetic neuropathy: what went wrong, what went right, and what does the future hold?

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12 December 2020

Neurotrophins and their receptors: a convergence point for many signalling pathways

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12 December 2020

Trk receptors: roles in neuronal signal transduction

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12 December 2020

Neurotrophic factors as novel therapeutics for neuropathic pain

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12 December 2020

Intrathecal nerve growth factor restores opioid effectiveness in an animal model of neuropathic pain

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12 December 2020

Effects of mouse tumor transplantation on the nervous system

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12 December 2020

Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product

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12 December 2020

Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation

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12 December 2020

The amino terminus of nerve growth factor is involved in the interaction with the receptor tyrosine kinase p140trkA.

1 reference

12 December 2020

Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system.

1 reference

12 December 2020

Contribution of protein kinase C to central sensitization and persistent pain following tissue injury

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12 December 2020

Long-lasting rescue of age-associated deficits in cognition and the CNS cholinergic phenotype by a partial agonist peptidomimetic ligand of TrkA.

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12 December 2020

Cell signaling and the genesis of neuropathic pain

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12 December 2020

Recombinant human nerve growth factor with a marked activity in vitro and in vivo.

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12 December 2020

Neurotrophins: mediators and modulators of pain.

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12 December 2020

Functional mimetics of neurotrophins and their receptors

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12 December 2020

Nerve growth factor in treatment and pathogenesis of Alzheimer's disease.

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12 December 2020

Antibodies to nerve growth factor reverse established tactile allodynia in rodent models of neuropathic pain without tolerance

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12 December 2020

Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease

1 reference

12 December 2020

The neuropathic pain triad: neurons, immune cells and glia

1 reference

12 December 2020

New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor

1 reference

12 December 2020

Regulation of axonal caliber, neurofilament content, and nuclear localization in mature sensory neurons by nerve growth factor

1 reference

12 December 2020

The in vitro biological effect of nerve growth factor is inhibited by synthetic peptides

1 reference

12 December 2020

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

1 reference

12 December 2020

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

1 reference

12 December 2020

The nerve growth factor 35 years later

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12 December 2020

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

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12 December 2020

The response of chick sensory neurons to brain-derived neurotrophic factor.

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12 December 2020

Improved spectral resolution in cosy 1H NMR spectra of proteins via double quantum filtering

1 reference

12 December 2020

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

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12 December 2020

Structural determinants of neurotrophin action.

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12 December 2020

Nerve growth factor: structure/function relationships

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12 December 2020

Alteration of NH2-terminal residues of nerve growth factor affects activity and Trk binding without affecting stability or conformation

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12 December 2020

Small peptide mimics of nerve growth factor bind TrkA receptors and affect biological responses

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12 December 2020

Mutagenesis identifies amino-terminal residues of nerve growth factor necessary for Trk receptor binding and biological activity.

1 reference

12 December 2020

Quantitative assessment of tactile allodynia in the rat paw

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12 December 2020

The carboxyl terminus of nerve growth factor is required for biological activity.

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12 December 2020

Nerve growth factor alleviates a painful peripheral neuropathy in rats

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12 December 2020

Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF.

1 reference

12 December 2020

Two restricted sites on the surface of the nerve growth factor molecule independently determine specific TrkA receptor binding and activation

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12 December 2020

Synthetic NGF peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism.

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12 December 2020

The role of the nerve growth factor carboxyl terminus in receptor binding and conformational stability

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12 December 2020

A second determinant of binding to the p75 neurotrophin receptor revealed by alanine-scanning mutagenesis of a conserved loop in nerve growth factor

1 reference

12 December 2020

High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the Trk receptors

1 reference

12 December 2020

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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12 December 2020

Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate.

1 reference

12 December 2020

10.1523/JNEUROSCI.5201-07.2008

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670672&resulttype=core&format=json

16 May 2020

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16 May 2020

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