The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage (Q46756266)

24 December 2017

title

The PDAPP mouse model of Alzheimer's disease: locus coeruleus neuronal shrinkage (English)

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24 December 2017

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Dwight C German

1

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24 December 2017

Omar Nelson

2

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24 December 2017

Fen Liang

3

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24 December 2017

Chang-Lin Liang

4

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24 December 2017

Dora Games

5

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24 December 2017

language of work or name

English

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publication date

1 November 2005

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24 December 2017

The Journal of Comparative Neurology

published in

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24 December 2017

volume

492

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24 December 2017

issue

4

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24 December 2017

page(s)

469-476

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24 December 2017

Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

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PROGRESSIVE SUPRANUCLEAR PALSY. A HETEROGENEOUS DEGENERATION INVOLVING THE BRAIN STEM, BASAL GANGLIA AND CEREBELLUM WITH VERTICAL GAZE AND PSEUDOBULBAR PALSY, NUCHAL DYSTONIA AND DEMENTIA.

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Alterations in catecholamine neurons of the locus coeruleus in senile dementia of the Alzheimer type and in Parkinson's disease with and without dementia and depression.

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Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex.

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Disease-specific patterns of locus coeruleus cell loss

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Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease

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Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

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7 January 2021

Loss of pigmented dopamine-beta-hydroxylase positive cells from locus coeruleus in senile dementia of Alzheimer's type.

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7 January 2021

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

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7 January 2021

Presenile appearance of abundant Alzheimer's neurofibrillary tangles without senile plaques in the brain in myotonic dystrophy.

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7 January 2021

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

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7 January 2021

Efferent projections of nucleus locus coeruleus: morphologic subpopulations have different efferent targets

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7 January 2021

Neurofibrillary tangles in Niemann-Pick disease type C

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Noradrenergic mechanisms in neurodegenerative diseases: a theory

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7 January 2021

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease

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BDNF is necessary for maintenance of noradrenergic innervations in the aged rat brain

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Central Catecholamine Neuron Systems: Anatomy and Physiology of the Norepinephrine and Epinephrine Systems

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Glial cell line-derived neurotrophic factor is essential for neuronal survival in the locus coeruleus-hippocampal noradrenergic pathway

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7 January 2021

Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

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7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

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7 January 2021

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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7 January 2021

Cell loss in the locus coeruleus in senile dementia of Alzheimer type.

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7 January 2021

Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.

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7 January 2021

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

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7 January 2021

Plaques, tangles and dementia. A quantitative study.

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7 January 2021

Reorganization of cholinergic terminals in the cerebral cortex and hippocampus in transgenic mice carrying mutated presenilin-1 and amyloid precursor protein transgenes.

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7 January 2021

Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases

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7 January 2021

Identifiers

DOI

10.1002/CNE.20744

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24 December 2017

PubMed ID

16228992

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24 December 2017