Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels. (Q46786077)

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scientific article published in April 2007

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English	Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels.	scientific article published in April 2007

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scholarly article

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29 December 2019

Dietary docosahexaenoic acid and docosapentaenoic acid ameliorate amyloid-beta and tau pathology via a mechanism involving presenilin 1 levels (English)

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29 December 2019

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Hilda Martínez-Coria

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29 December 2019

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Kim N Green

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29 December 2019

Hasan Khashwji

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Eileen B Hall

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29 December 2019

Karin A Yurko-Mauro

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Lorie Ellis

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29 December 2019

Frank M LaFerla

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1 April 2007

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29 December 2019

Journal of Neuroscience

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29 December 2019

4385-4395

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29 December 2019

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

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Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

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Transthyretin binds amyloid beta peptides, Abeta1-42 and Abeta1-40 to form complex in the autopsied human kidney - possible role of transthyretin for abeta sequestration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

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Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Short-term administration of omega 3 fatty acids from fish oil results in increased transthyretin transcription in old rat hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Low serum cholesteryl ester-docosahexaenoic acid levels in Alzheimer's disease: a case-control study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

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PREPARATION OF FATTY ACID METHYL ESTERS AND DIMETHYLACETALS FROM LIPIDS WITH BORON FLUORIDE--METHANOL

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Cyclooxygenase (COX)-2 and COX-1 Potentiate β-Amyloid Peptide Generation through Mechanisms That Involve γ-Secretase Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

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Deoxynivalenol-induced mitogen-activated protein kinase phosphorylation and IL-6 expression in mice suppressed by fish oil.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary supplementation with melatonin reduces levels of amyloid beta-peptides in the murine cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin 1 stabilizes the C-terminal fragment of the amyloid precursor protein independently of gamma-secretase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Docosahexaenoic acid protects from dendritic pathology in an Alzheimer's disease mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids increase presenilin-1 levels and [gamma]-secretase activity in PSwt-1 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of non-phosphorylated and phosphorylated tau by thrombin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation amyloid beta-protein 42 production by interfering with transcript of presenilin 1 gene with siRNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age- and region-dependent alterations in Abeta-degrading enzymes: implications for Abeta-induced disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic administration of docosahexaenoic acid ameliorates the impairment of spatial cognition learning ability in amyloid beta-infused rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of A beta precursors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

c-jun N-terminal kinase hyperphosphorylates R406W tau at the PHF-1 site during mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eicosapentaenoic acid and docosahexaenoic acid modulate mitogen-activated protein kinase activity in endothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease: the Framingham Heart Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arachidonic and docosahexanoic acid content of bovine brain myelin: implications for the pathogenesis of multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary omega-3 fatty acids and accumulation of docosahexaenoic acid in rod photoreceptor cells of the retina and at synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single plate separation of lung phospholipids including disaturated phosphatidylcholine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical distribution of peptidergic and cholinergic fibers in the human amygdala: their depletion in Alzheimer's disease and morphologic alteration in non-demented elderly with numerous senile plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cdc2-related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New piece in Alzheimer's puzzle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivating kinase/p38 phosphorylates tau protein in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diagnostic criteria for neuropathologic assessment of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/17442823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0055-07.2007

1 reference

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29 December 2019

1 reference

Europe PubMed Central

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29 December 2019

1 reference

Europe PubMed Central

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29 December 2019

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