The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of A beta precursors. (Q51810919)

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15 January 2020

title

The cytoplasmic sequence of E-cadherin promotes non-amyloidogenic degradation of A beta precursors (English)

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15 January 2020

4

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15 January 2020

author name string

Georgia Agiostratidou

1

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15 January 2020

Rosa Miñana Muros

2

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15 January 2020

Junichi Shioi

3

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15 January 2020

Nikolaos K Robakis

5

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15 January 2020

language of work or name

English

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publication date

26 January 2006

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Journal of Neurochemistry

15 January 2020

number of pages

7

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based on heuristic

inferred from page(s)

published in

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15 January 2020

volume

96

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15 January 2020

issue

4

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15 January 2020

page(s)

1182-1188

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Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells

15 January 2020

cites work

1 reference

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Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage

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Presenilin 1 mutations activate gamma 42-secretase but reciprocally inhibit epsilon-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

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Secretion and accumulation of Alzheimer's beta-protein by cultured vascular smooth muscle cells from old and young dogs.

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Inhibition of beta-amyloid formation identifies proteolytic precursors and subcellular site of catabolism

21 January 2018

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Identity and function of γ‐secretase

21 January 2018

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Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression

21 January 2018

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Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation.

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A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

21 January 2018

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A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

21 January 2018

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Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease.

21 January 2018

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Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

21 January 2018

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Presenilin-1, Nicastrin, Amyloid Precursor Protein, and γ-Secretase Activity Are Co-localized in the Lysosomal Membrane

21 January 2018

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Inhibition of beta-catenin-mediated transactivation by cadherin derivatives

21 January 2018

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Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch

21 January 2018

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A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis

21 January 2018

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

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A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

21 January 2018

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Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

21 January 2018

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A Novel γ-Secretase Assay Based on Detection of the Putative C-terminal Fragment-γ of Amyloid β Protein Precursor

21 January 2018

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