Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences. (Q48096332)

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25 March 2020

title

Human CST Prefers G-Rich but Not Necessarily Telomeric Sequences (English)

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25 March 2020

2

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25 March 2020

author name string

Robert A Hom

series ordinal

1

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language of work or name

English

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publication date

2 August 2017

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25 March 2020

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25 March 2020

volume

56

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25 March 2020

issue

32

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page(s)

4210-4218

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Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

25 March 2020

cites work

1 reference

12 December 2020

A new model for Schizosaccharomyces pombe telomere recognition: the telomeric single-stranded DNA-binding activity of Pot11-389.

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12 December 2020

Structure and conformational change of a replication protein A heterotrimer bound to ssDNA

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12 December 2020

Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection

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12 December 2020

The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch

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12 December 2020

Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres

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12 December 2020

Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes

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12 December 2020

Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes

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12 December 2020

The POT1-TPP1 telomere complex is a telomerase processivity factor

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12 December 2020

Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres

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12 December 2020

CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion

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12 December 2020

Delineation of the high-affinity single-stranded telomeric DNA-binding domain of Saccharomyces cerevisiae Cdc13.

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12 December 2020

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12 December 2020

Structure and function of the telomeric CST complex

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12 December 2020

Structure prediction-driven genetics in Saccharomyces cerevisiae identifies an interface between the t-RPA proteins Stn1 and Ten1

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12 December 2020

TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

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12 December 2020

Human CST promotes telomere duplex replication and general replication restart after fork stalling

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12 December 2020

Functional characterization of human CTC1 mutations reveals novel mechanisms responsible for the pathogenesis of the telomere disease Coats plus

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12 December 2020

Interactions of human replication protein A with oligonucleotides

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12 December 2020

Single-stranded DNA-binding proteins: multiple domains for multiple functions

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12 December 2020

Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions

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12 December 2020

Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells.

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12 December 2020

Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70

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12 December 2020

STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST Function.

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12 December 2020

Structural and functional analysis of the human POT1-TPP1 telomeric complex

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12 December 2020

Human TEN1 maintains telomere integrity and functions in genome-wide replication restart

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12 December 2020

Molecular basis of telomere syndrome caused by CTC1 mutations

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12 December 2020

Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain

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12 December 2020

Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer

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12 December 2020

Nonspecific Recognition Is Achieved in Pot1pC through the Use of Multiple Binding Modes

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12 December 2020

Conserved structure for single-stranded telomeric DNA recognition

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12 December 2020

Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA

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12 December 2020

Telomerase and telomere-associated proteins: structural insights into mechanism and evolution

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12 December 2020

Mutations in CTC1, encoding the CTS telomere maintenance complex component 1, cause cerebroretinal microangiopathy with calcifications and cysts

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12 December 2020

How shelterin protects mammalian telomeres

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12 December 2020

MultiBac complexomics

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12 December 2020

RPA and POT1: friends or foes at telomeres?

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12 December 2020

Mutations in the telomere capping complex in bone marrow failure and related syndromes

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12 December 2020

The human CST complex is a terminator of telomerase activity

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12 December 2020

The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain

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12 December 2020

A dynamic model for replication protein A (RPA) function in DNA processing pathways

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12 December 2020

Human CST Facilitates Genome-wide RAD51 Recruitment to GC-Rich Repetitive Sequences in Response to Replication Stress

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12 December 2020

Structure of the Human Telomeric Stn1-Ten1 Capping Complex

1 reference

12 December 2020

Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus

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12 December 2020

RPA-like proteins mediate yeast telomere function

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12 December 2020

A new structural framework for integrating replication protein A into DNA processing machinery.

1 reference

12 December 2020

RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway

1 reference

12 December 2020

Human CST abundance determines recovery from diverse forms of DNA damage and replication stress

1 reference

12 December 2020

Identification of the determinants for the specific recognition of single-strand telomeric DNA by Cdc13

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12 December 2020

The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex

1 reference

12 December 2020

The mechanism of action of an accessory protein for DNA polymerase alpha/primase

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12 December 2020

Site-directed mutagenesis reveals the thermodynamic requirements for single-stranded DNA recognition by the telomere-binding protein Cdc13.

1 reference

12 December 2020

Purification and properties of an accessory protein for DNA polymerase alpha/primase

1 reference

12 December 2020

A DNA polymerase-{alpha}⋅primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells

1 reference

12 December 2020

Identification of the single-strand telomeric DNA binding domain of the Saccharomyces cerevisiae Cdc13 protein

1 reference

12 December 2020

Human CST has independent functions during telomere duplex replication and C-strand fill-in

1 reference

12 December 2020

Sequence-specific binding to telomeric DNA is not a conserved property of the Cdc13 DNA binding domain

1 reference

12 December 2020

Schizosaccharomyces pombe protection of telomeres 1 utilizes alternate binding modes to accommodate different telomeric sequences

1 reference

12 December 2020

The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein

1 reference

12 December 2020

MultiBac: expanding the research toolbox for multiprotein complexes.

1 reference

12 December 2020

Evolution of CST function in telomere maintenance

1 reference

12 December 2020

Practical strategies for the evaluation of high-affinity protein/nucleic acid interactions

1 reference

12 December 2020

10.1021/ACS.BIOCHEM.7B00584

Identifiers

DOI

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25 March 2020

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25 March 2020

PubMed publication ID

28726394

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