Human CST promotes telomere duplex replication and general replication restart after fork stalling (Q34292284)

1 August 2017

title

Human CST promotes telomere duplex replication and general replication restart after fork stalling (English)

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1 August 2017

2

Feng Wang

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1 August 2017

6

Woodring E Wright

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1 August 2017

Jason A Stewart

1

1 reference

1 August 2017

Mary F Chaiken

3

1 reference

1 August 2017

Christopher Kasbek

4

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1 August 2017

Paul D Chastain

5

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1 August 2017

Carolyn M Price

7

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1 August 2017

language of work or name

English

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publication date

3 August 2012

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1 August 2017

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1 August 2017

volume

31

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1 August 2017

issue

17

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1 August 2017

page(s)

3537-3549

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describes a project that uses

1 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3433780/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Human telomeres replicate using chromosome-specific, rather than universal, replication programs

6 July 2018

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Mutations in CTC1, encoding the CTS telomere maintenance complex component 1, cause cerebroretinal microangiopathy with calcifications and cysts

6 July 2018

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Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus

6 July 2018

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Xenopus laevis Ctc1-Stn1-Ten1 (xCST) protein complex is involved in priming DNA synthesis on single-stranded DNA template in Xenopus egg extract

6 July 2018

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Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast.

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RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance

6 July 2018

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6 July 2018

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6 July 2018

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BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping

6 July 2018

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6 July 2018

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CST meets shelterin to keep telomeres in check

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6 July 2018

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Telomeres: structures in need of unwinding

6 July 2018

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FEN1 ensures telomere stability by facilitating replication fork re-initiation

6 July 2018

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TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo

6 July 2018

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6 July 2018

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Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress

6 July 2018

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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

6 July 2018

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6 July 2018

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TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression

6 July 2018

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Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

6 July 2018

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POT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation

6 July 2018

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Conserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotes

6 July 2018

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RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway

6 July 2018

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Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis

6 July 2018

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Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

6 July 2018

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Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells

6 July 2018

1 reference

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TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: implications for a replication restart-based mechanism for ATR checkpoint activation

6 July 2018

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OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation

6 July 2018

1 reference

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6 July 2018

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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities

6 July 2018

1 reference

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Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition

6 July 2018

1 reference

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Yeast telomere capping protein Stn1 overrides DNA replication control through the S phase checkpoint

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

A DNA polymerase-{alpha}⋅primase cofactor with homology to replication protein A-32 regulates DNA replication in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

How shelterin protects mammalian telomeres

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

How telomeres are replicated

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

6 July 2018

Chromosome fragile sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

The ATR pathway: fine-tuning the fork

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

Human telomeres have different overhang sizes at leading versus lagging strands

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

Hydroxyurea Arrests DNA Replication by a Mechanism That Preserves Basal dNTP Pools

6 July 2018

1 reference

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Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

6 July 2018

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Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects

6 July 2018

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Cdc13 delivers separate complexes to the telomere for end protection and replication

6 July 2018

1 reference

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Cdc13 both positively and negatively regulates telomere replication

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

DNA polymerase epsilon: aphidicolin inhibition and the relationship between polymerase and exonuclease activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

The mechanism of action of an accessory protein for DNA polymerase alpha/primase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

Purification and properties of an accessory protein for DNA polymerase alpha/primase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433780

ATR and H2AX cooperate in maintaining genome stability under replication stress

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.215

Checkpoint regulation of replication dynamics in UV-irradiated human cells.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.215

Replication Stress Interferes with Histone Recycling and Predeposition Marking of New Histones

21 January 2018

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Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.215

21 January 2018

Identifiers

DOI

10.1038/EMBOJ.2012.215

1 reference

1 August 2017

1 reference

1 August 2017

1 reference