Rho family GTPase inhibition reveals opposing effects of mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and Janus kinase/signal transducer and activator of transcription signaling cascades on neuronal survival (Q48547144)

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English	Rho family GTPase inhibition reveals opposing effects of mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and Janus kinase/signal transducer and activator of transcription signaling cascades on neuronal survival	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Rho family GTPase inhibition reveals opposing effects of mitogen-activated protein kinase kinase/extracellular signal-regulated kinase and Janus kinase/signal transducer and activator of transcription signaling cascades on neuronal survival (English)

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

author name string

F Alexandra Loucks

1

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Shoshona S Le

2

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PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Angela K Zimmermann

3

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Kristen R Ryan

4

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Holger Barth

5

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Klaus Aktories

6

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Daniel A Linseman

7

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12 February 2018

http://europepmc.org/abstract/MED/16686690

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publication date

1 May 2006

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Journal of Neurochemistry

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PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

97

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PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

4

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PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

957-967

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Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

Novel mechanism for gonadotropin-releasing hormone neuronal migration involving Gas6/Ark signaling to p38 mitogen-activated protein kinase

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Suppressors of cytokine signaling (SOCS): inhibitors of the JAK/STAT pathway

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Genes regulated in neurons undergoing transcription-dependent apoptosis belong to signaling pathways rather than the apoptotic machinery

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Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes

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Rho GTPases in cell biology

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Opposite regulation of the mitochondrial apoptotic pathway by C2-ceramide and PACAP through a MAP-kinase-dependent mechanism in cerebellar granule cells

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The role of the Rho GTPases in neuronal development

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Ca2+-dependent regulation of rho GTPases triggers turning of nerve growth cones.

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Large clostridial cytotoxins

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Glucosylation of Rho proteins by Clostridium difficile toxin B.

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A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death

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Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

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ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis.

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Inhibition of Rac GTPase triggers a c-Jun- and Bim-dependent mitochondrial apoptotic cascade in cerebellar granule neurons

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Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

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Gene and protein profiling of the response of MA-10 Leydig tumor cells to human chorionic gonadotropin

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An essential role for Rac/Cdc42 GTPases in cerebellar granule neuron survival

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Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

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High-throughput immunoblotting. Ubiquitiin-like protein ISG15 modifies key regulators of signal transduction

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Blockade of HMG-CoA reductase activity causes changes in microtubule-stabilizing protein tau via suppression of geranylgeranylpyrophosphate formation: implications for Alzheimer's disease

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Rho GTPases regulate axon growth through convergent and divergent signaling pathways.

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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Ras, Rap, and Rac small GTP-binding proteins are targets for Clostridium sordellii lethal toxin glucosylation.

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STAT-1 interacts with p53 to enhance DNA damage-induced apoptosis

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Identifiers

10.1111/J.1471-4159.2006.03802.X

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 February 2018

http://europepmc.org/abstract/MED/16686690

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