IGF-1 and pAKT signaling promote hippocampal CA1 neuronal survival following injury to dentate granule cells (Q48570233)

3 July 2019

title

IGF-1 and pAKT signaling promote hippocampal CA1 neuronal survival following injury to dentate granule cells (English)

1 reference

3 July 2019

3

G Jean Harry

1 reference

3 July 2019

author name string

Robert N Wine

series ordinal

1

1 reference

3 July 2019

Christopher A McPherson

series ordinal

2

1 reference

3 July 2019

publication date

28 May 2009

1 reference

3 July 2019

published in

Neurotoxicity Research

1 reference

3 July 2019

volume

16

1 reference

3 July 2019

issue

3

1 reference

3 July 2019

page(s)

280-292

1 reference

3 July 2019

ATP mediates rapid microglial response to local brain injury in vivo

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12640-009-9060-Y

The effects of IGF-1 treatment after hypoxic-ischemic brain injury in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-009-9060-Y

Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-009-9060-Y

Intraventricular administration of insulin and IGF-1 in transient forebrain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-009-9060-Y

IGF-1 modulates N and L calcium channels in a PI 3-kinase-dependent manner

21 January 2018

1 reference

12 December 2020

A rose by any other name? The potential consequences of microglial heterogeneity during CNS health and disease

1 reference

12 December 2020

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

12 December 2020

Insulin-like growth factor 1 prevents neuronal cell death induced by corticosterone through activation of the PI3k/Akt pathway

1 reference

12 December 2020

Hypoxia induces an autocrine-paracrine survival pathway via platelet-derived growth factor (PDGF)-B/PDGF-beta receptor/phosphatidylinositol 3-kinase/Akt signaling in RN46A neuronal cells

1 reference

12 December 2020

IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage

1 reference

12 December 2020

Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors

1 reference

12 December 2020

IGF-I and microglia/macrophage proliferation in the ischemic mouse brain

1 reference

12 December 2020

Neuronal protection from glucose deprivation via modulation of glucose transport and inhibition of apoptosis: a role for the insulin-like growth factor system

1 reference

12 December 2020

Regulation of chemokines and chemokine receptors after experimental closed head injury

1 reference

12 December 2020

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

12 December 2020

Insulin-like growth factor I rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death

1 reference

12 December 2020

Akt-dependent potentiation of L channels by insulin-like growth factor-1 is required for neuronal survival

1 reference

12 December 2020

Like cops on the beat: the active role of resting microglia

1 reference

12 December 2020

Differential trophic effects of basic fibroblast growth factor, insulin-like growth factor-1, and neurotrophin-3 on striatal neurons in culture

1 reference

12 December 2020

Dentate granule neuron apoptosis and glia activation in murine hippocampus induced by trimethyltin exposure

1 reference

12 December 2020

Akt-dependent transformation: there is more to growth than just surviving

1 reference

12 December 2020

Chemical-induced hippocampal neurodegeneration and elevations in TNFalpha, TNFbeta, IL-1alpha, IP-10, and MCP-1 mRNA in osteopetrotic (op/op) mice

1 reference

12 December 2020

Microglia and chemokines in infectious diseases of the nervous system: views and reviews

1 reference

12 December 2020

Dentate gyrus: alterations that occur with hippocampal injury

1 reference

12 December 2020

Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.

1 reference

12 December 2020

Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons.

1 reference

12 December 2020

Regulation of Fas antigen (Fas, CD95)-mediated apoptosis of bovine granulosa cells by serum and growth factors

1 reference

12 December 2020

Fibroblast growth factor-2 and -4 promote the proliferation of bone marrow mesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways

1 reference

12 December 2020

Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.

1 reference

12 December 2020

Neuroprotective effect of exogenous microglia in global brain ischemia.

1 reference

12 December 2020

Expression of the activating transcription factor 3 prevents c-Jun N-terminal kinase-induced neuronal death by promoting heat shock protein 27 expression and Akt activation.

1 reference

12 December 2020

IGF-1 receptor-mediated ERK/MAPK signaling couples status epilepticus to progenitor cell proliferation in the subgranular layer of the dentate gyrus.

1 reference

12 December 2020

Trimethyltin-induced apoptosis is associated with upregulation of inducible nitric oxide synthase and Bax in a hippocampal cell line

1 reference

12 December 2020

Mechanisms of disease: the PI3K-Akt-PTEN signaling node--an intercept point for the control of angiogenesis in brain tumors

1 reference

12 December 2020

Akt activation protects hippocampal neurons from apoptosis by inhibiting transcriptional activity of p53.

1 reference

12 December 2020

Cellular survival: a play in three Akts

1 reference

12 December 2020

Motility and ramification of human fetal microglia in culture: an investigation using time-lapse video microscopy and image analysis

1 reference

12 December 2020

Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons

1 reference

12 December 2020

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

12 December 2020

The type 1 interleukin 1 receptor is not required for the death of murine hippocampal dentate granule cells and microglia activation

1 reference

12 December 2020

A new concept in neurodegeneration: TNFalpha is a silencer of survival signals

1 reference

12 December 2020

Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons

1 reference

12 December 2020

AKT activation in human glioblastomas enhances proliferation via TSC2 and S6 kinase signaling.

1 reference

12 December 2020

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

1 reference

12 December 2020

Insulin-like growth factor-I prevents apoptosis in neurons after nerve growth factor withdrawal

1 reference

12 December 2020

Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.

1 reference

12 December 2020

Neuropathology of mouse hippocampus in acute trimethyltin intoxication.

1 reference

12 December 2020

Regional hippocampal differences in AKT survival signaling across the lifespan: implications for CA1 vulnerability with aging

1 reference

12 December 2020

Microglia as neuroprotective, immunocompetent cells of the CNS.

1 reference

12 December 2020

Pharmacogenomic profiling of the PI3K/PTEN-AKT-mTOR pathway in common human tumors

1 reference

12 December 2020

Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans

1 reference

12 December 2020

Age-dependent cytokine responses: trimethyltin hippocampal injury in wild-type, APOE knockout, and APOE4 mice

1 reference

12 December 2020

Transforming growth factor beta as a neuronoglial signal during peripheral nervous system response to injury.

1 reference

12 December 2020

Sub-regional hippocampal vulnerability in various animal models leading to cognitive dysfunction

1 reference

12 December 2020

Intracerebroventricular injection of microglia protects against focal brain ischemia

1 reference

12 December 2020

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

1 reference

12 December 2020

Effect of riluzole on the neurological and neuropathological changes in an animal model of cardiac arrest-induced movement disorder.

1 reference

12 December 2020

Hippocampal neurons in pre-clinical Alzheimer's disease.

1 reference

12 December 2020

Microglia provide neuroprotection after ischemia

1 reference

12 December 2020

Insulin-like growth factor-1 is a potent neuronal rescue agent after hypoxic-ischemic injury in fetal lambs

1 reference

12 December 2020

The involvement of phosphoinositid 3-kinase/Akt pathway in the activation of hypoxia-inducible factor-1alpha in the developing rat brain after hypoxia-ischemia

1 reference

12 December 2020

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

1 reference

12 December 2020

Molecular profiles of mRNA levels in laser capture microdissected murine hippocampal regions differentially responsive to TMT-induced cell death

1 reference

12 December 2020

Autocrine-paracrine regulation of hippocampal neuron survival by IGF-1 and the neurotrophins BDNF, NT-3 and NT-4

1 reference

12 December 2020

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

1 reference

12 December 2020

Expression and changes of endogenous insulin-like growth factor-1 in neurons and glia in the gerbil hippocampus and dentate gyrus after ischemic insult

1 reference

12 December 2020

Early loss of somatostatin neurons in dentate hilus after cerebral ischemia in the rat precedes CA-1 pyramidal cell loss

1 reference

12 December 2020

Rescue of TNFalpha-inhibited neuronal cells by IGF-1 involves Akt and c-Jun N-terminal kinases

1 reference

12 December 2020

Plasticity of developing and adult dorsal root ganglion neurons as revealed in vitro

1 reference

12 December 2020

Potentiation of neuronal L calcium channels by IGF-1 requires phosphorylation of the alpha1 subunit on a specific tyrosine residue

1 reference

12 December 2020

Microglia-derived IGF-2 prevents TNFalpha induced death of mature oligodendrocytes in vitro

1 reference

12 December 2020

Microglia: a sensor for pathological events in the CNS

1 reference

12 December 2020

E2-induced degradation of uterine insulin receptor substrate-2: requirement for an IGF-I-stimulated, proteasome-dependent pathway

1 reference

12 December 2020

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

12 December 2020

The three-dimensional organization of the hippocampal formation: a review of anatomical data

1 reference

12 December 2020

TGF beta 1 expression is initiated in adult auditory neurons by sectioning of the auditory nerve

1 reference

12 December 2020

Developmental neuropathology of organotin compounds.

1 reference

12 December 2020

The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change

1 reference

12 December 2020

Metabolic catastrophe as a means to cancer cell death

1 reference

12 December 2020

Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.

1 reference

12 December 2020

The IGF axis and programmed cell death

1 reference

12 December 2020

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

1 reference

12 December 2020

The effects of insulin-like growth factor (IGF)-1, IGF-2, and des-IGF-1 on neuronal loss after hypoxic-ischemic brain injury in adult rats: evidence for a role for IGF binding proteins

1 reference

12 December 2020

Alterations in cyclin A, B, and D1 in mouse dentate gyrus following TMT-induced hippocampal damage

1 reference

12 December 2020

Cellular localization and temporal elevation of tumor necrosis factor-alpha, interleukin-1 alpha, and transforming growth factor-beta 1 mRNA in hippocampal injury response induced by trimethyltin.

1 reference

12 December 2020

Chemokines and glial cells: a complex network in the central nervous system.

1 reference

12 December 2020

Tumor necrosis factor p55 and p75 receptors are involved in chemical-induced apoptosis of dentate granule neurons

1 reference

12 December 2020

Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy

1 reference

12 December 2020

10.1007/S12640-009-9060-Y

Identifiers

DOI

1 reference

3 July 2019

PMC publication ID

6276784

1 reference

3 July 2019

PubMed publication ID

19526277

1 reference

3 July 2019