mTOR is required for asymmetric division through small GTPases in mouse oocytes. (Q48653493)

13 February 2018

title

mTOR is required for asymmetric division through small GTPases in mouse oocytes. (English)

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13 February 2018

author name string

Seung-Eun Lee

1

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13 February 2018

Shao-Chen Sun

2

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13 February 2018

Hyun-Yong Choi

3

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13 February 2018

Sang-Jun Uhm

4

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13 February 2018

Nam-Hyung Kim

5

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13 February 2018

publication date

1 May 2012

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13 February 2018

Molecular Reproduction and Development

published in

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13 February 2018

volume

79

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issue

5

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13 February 2018

page(s)

356-366

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Actin filaments: key players in the control of asymmetric divisions in mouse oocytes.

cites work

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Inhibition of S6 kinase by rapamycin blocks maturation of Rana dybowskii oocytes.

21 January 2018

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Positioning to get out of meiosis: the asymmetry of division.

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The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

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Chromatin-mediated cortical granule redistribution is responsible for the formation of the cortical granule-free domain in mouse eggs

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Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

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Genes required for mitotic spindle assembly in Drosophila S2 cells

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Defining the role of mTOR in cancer

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The pharmacology of mTOR inhibition

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Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

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Mammalian Rho GTPases: new insights into their functions from in vivo studies

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Tor signalling in bugs, brain and brawn

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

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Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro

21 January 2018

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Inactivation of MAPK affects centrosome assembly, but not actin filament assembly, in mouse oocytes maturing in vitro.

21 January 2018

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Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

21 January 2018

1 reference

Drosophila S6 kinase: a regulator of cell size

21 January 2018

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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

21 January 2018

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Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

21 January 2018

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mTOR and cancer: insights into a complex relationship

21 January 2018

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

21 January 2018

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Dynamic events are differently mediated by microfilaments, microtubules, and mitogen-activated protein kinase during porcine oocyte maturation and fertilization in vitro

21 January 2018

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Regulation of dynamic events by microfilaments during oocyte maturation and fertilization

21 January 2018

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Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response

21 January 2018

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Tor kinases are in distinct membrane-associated protein complexes in Saccharomyces cerevisiae

21 January 2018

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TOR signaling in growth and metabolism

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Expanding mTOR signaling

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Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.

21 January 2018

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Regulation of cellular growth by the Drosophila target of rapamycin dTOR

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21 January 2018

Identifiers

DOI

10.1002/MRD.22035

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13 February 2018

PubMed ID

22407942

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13 February 2018