Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB. (Q48906070)

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scientific article published in September 2011

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English	Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB.	scientific article published in September 2011

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scholarly article

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB. (English)

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

experimental autoimmune encephalomyelitis

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transmembrane protein

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6

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16 February 2018

http://europepmc.org/abstract/MED/21908876

David E. Szymkowski

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http://europepmc.org/abstract/MED/21908876

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object named as

Michael Karin

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Europe PubMed Central

16 February 2018

author name string

Era Taoufik

1

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

Vivian Tseveleki

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

Seung Y Chu

3

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

Theodore Tselios

4

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Europe PubMed Central

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http://europepmc.org/abstract/MED/21908876

Lesley Probert

8

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

language of work or name

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publication date

1 September 2011

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

134

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2722-2735

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Pt 9

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http://europepmc.org/abstract/MED/21908876

Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

The receptor for tumor necrosis factor on murine astrocytes: characterization, intracellular degradation, and regulation by cytokines and Theiler's murine encephalomyelitis virus.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Control of synaptic strength by glial TNFalpha

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Colony stimulating factor-1 potentiates neuronal survival in cerebral cortex ischemic lesion.

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Distribution and characterization of tumor necrosis factor-alpha-like immunoreactivity in the murine central nervous system

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

NF-kappa B as a therapeutic target in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

GRO-alpha and CXCR2 in the human fetal brain and multiple sclerosis lesions.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Membrane TNF confers protection to acute mycobacterial infection

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Missing pieces in the NF-kappaB puzzle

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Hypoxia-like tissue injury as a component of multiple sclerosis lesions

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE).

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pat

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Essential role for TrkB receptors in hippocampus-mediated learning

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Demyelination occurring during anti-tumor necrosis factor alpha therapy for inflammatory arthritides

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Recombinant human tumor necrosis factor receptor (p75) Fc fusion protein (TNFR:Fc) in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Soluble TNF mediates the transition from pulmonary inflammation to fibrosis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Soluble TNF, but not membrane TNF, is critical in LPS-induced hepatitis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Dominant-negative tumor necrosis factor protects from Mycobacterium bovis Bacillus Calmette Guérin (BCG) and endotoxin-induced liver injury without compromising host immunity to BCG and Mycobacterium tuberculosis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Critical role for NF-kappaB-induced JunB in VEGF regulation and tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Anti?tumor necrosis factor therapy abrogates autoimmune demyelination

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Dual role of tumor necrosis factor alpha in brain injury

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Interleukin-1 and inflammatory neurodegeneration

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Inactivation of TNF signaling by rationally designed dominant-negative TNF variants

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Differential regulation of AMPA receptor and GABA receptor trafficking by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Tumor necrosis factor-alpha antagonists and neuropathy

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

FLIP(L) protects neurons against in vivo ischemia and in vitro glucose deprivation-induced cell death.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFkB and MAPK dependent pathways in rat astrocytes [corrected].

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Membrane tumor necrosis factor confers partial protection to Listeria infection

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Tumor necrosis factor signaling.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWR203

21 January 2018

Identifiers

10.1093/BRAIN/AWR203

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21908876

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