Preclinical evaluation and reverse phase protein Array-based profiling of PI3K and MEK inhibitors in endometrial carcinoma in vitro. (Q49180082)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29426295%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

title

Preclinical evaluation and reverse phase protein Array-based profiling of PI3K and MEK inhibitors in endometrial carcinoma in vitro (English)

1 reference

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15 March 2020

main subject

endometrial carcinoma

1 reference

4

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15 March 2020

Gordon B. Mills

5

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15 March 2020

6

Bryan T Hennessy

1 reference

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15 March 2020

author name string

Ozlem Aslan

1

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15 March 2020

Mattia Cremona

2

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15 March 2020

Clare Morgan

3

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15 March 2020

language of work or name

English

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publication date

9 February 2018

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15 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29426295%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

volume

18

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15 March 2020

page(s)

168

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15 March 2020

issue

1

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https://scigraph.springernature.com/pub.10.1186/s12885-018-4035-0

15 March 2020

exact match

0 references

cites work

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A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation

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Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition

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GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway

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High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability

22 May 2018

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PIK3R1 (p85α) is somatically mutated at high frequency in primary endometrial cancer

22 May 2018

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In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models.

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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14 August 2018

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14 August 2018

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14 August 2018

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14 August 2018

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10.1186/S12885-018-4035-0

14 August 2018

Identifiers

DOI

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Dimensions Publication ID

15 March 2020

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15 March 2020

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