Preserving Salivary Gland Physiology against Genotoxic Damage - The Tousled Way. (Q49565489)

21 February 2018

title

Preserving Salivary Gland Physiology against Genotoxic Damage - The Tousled Way. (English)

1 reference

21 February 2018

Gulshan Sunavala-Dossabhoy

1 reference

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29383801%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Gulshan Sunavala-Dossabhoy

series ordinal

1

1 reference

21 February 2018

publication date

30 January 2018

1 reference

21 February 2018

published in

Oral Diseases

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29383801%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29383801%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29383801%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

1390-1398

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29383801%20AND%20SRC:MED&resulttype=core&format=json

Oral complications at 6 months after radiation therapy for head and neck cancer.

31 May 2020

cites work

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26 August 2018

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BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation.

26 August 2018

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Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.

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Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection.

26 August 2018

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Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability

26 August 2018

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Tousled-like kinase 2 regulates recovery from a DNA damage-induced G2 arrest

26 August 2018

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26 August 2018

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Tousled kinase activator, gallic acid, promotes homologous recombinational repair and suppresses radiation cytotoxicity in salivary gland cells

26 August 2018

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MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.

26 August 2018

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Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit

26 August 2018

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DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

26 August 2018

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Recombinant AAV9-TLK1B administration ameliorates fractionated radiation-induced xerostomia

26 August 2018

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Nek1 kinase associates with ATR-ATRIP and primes ATR for efficient DNA damage signaling

26 August 2018

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Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction

26 August 2018

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BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

26 August 2018

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Homologous recombination repairs secondary replication induced DNA double-strand breaks after ionizing radiation.

26 August 2018

1 reference

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Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

26 August 2018

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Prevention of radiation-induced salivary hypofunction following hKGF gene delivery to murine submandibular glands.

26 August 2018

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Adenoviral delivery of Tousled kinase for the protection of salivary glands against ionizing radiation damage.

26 August 2018

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The DNA Damage Response: Making It Safe to Play with Knives

26 August 2018

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

A systematic review of salivary gland hypofunction and xerostomia induced by cancer therapies: prevalence, severity and impact on quality of life

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Tousled kinase TLK1B mediates chromatin assembly in conjunction with Asf1 regardless of its kinase activity

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Human CtIP mediates cell cycle control of DNA end resection and double strand break repair

26 August 2018

1 reference

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Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining

26 August 2018

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Tousled homolog, TLK1, binds and phosphorylates Rad9; TLK1 acts as a molecular chaperone in DNA repair.

26 August 2018

1 reference

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ATR: an essential regulator of genome integrity

26 August 2018

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Rescue of salivary gland function after stem cell transplantation in irradiated glands

26 August 2018

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Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase

26 August 2018

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The DNA damage response: ten years after

26 August 2018

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26 August 2018

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26 August 2018

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Processing of 3'-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease

26 August 2018

1 reference

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PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

26 August 2018

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Recruitment of ATR-ATRIP, Rad17, and 9-1-1 complexes to DNA damage

26 August 2018

1 reference

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Role of mammalian Rad9 in genomic stability and ionizing radiation response.

26 August 2018

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Rapid activation of ATR by ionizing radiation requires ATM and Mre11

26 August 2018

1 reference

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The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks

26 August 2018

1 reference

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Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks

26 August 2018

1 reference

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Influence of double-strand-break repair pathways on radiosensitivity throughout the cell cycle in CHO cells.

26 August 2018

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Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1

26 August 2018

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TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators.

26 August 2018

1 reference

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Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA

26 August 2018

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A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells

26 August 2018

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26 August 2018

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Phosphorylation of Human Rad9 Is Required for Genotoxin-activated Checkpoint Signaling

26 August 2018

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Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint

26 August 2018

1 reference

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Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases

26 August 2018

1 reference

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A translationally regulated Tousled kinase phosphorylates histone H3 and confers radioresistance when overexpressed

26 August 2018

1 reference

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Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes

26 August 2018

1 reference

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Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication

26 August 2018

1 reference

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Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

The Tousled gene in A. thaliana encodes a protein kinase homolog that is required for leaf and flower development

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Differential requirements for Tousled-like kinases 1 and 2 in mammalian development

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

WRN regulates pathway choice between classical and alternative non-homologous end joining

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

53BP1 fosters fidelity of homology-directed DNA repair

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Sparing the region of the salivary gland containing stem cells preserves saliva production after radiotherapy for head and neck cancer.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication.

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

TAT-mediated delivery of Tousled protein to salivary glands protects against radiation-induced hypofunction

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Dose-effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6066457

Lack of WRN results in extensive deletion at nonhomologous joining ends

2 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29383801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29383801

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/ODI.12836

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29383801%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29383801%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference