I148M variant of PNPLA3 increases the susceptibility to non-alcoholic fatty liver disease caused by obesity and metabolic disorders. (Q50241143)

28 February 2018

http://europepmc.org/abstract/MED/26765961

title

I148M variant of PNPLA3 increases the susceptibility to non-alcoholic fatty liver disease caused by obesity and metabolic disorders. (English)

1 reference

28 February 2018

http://europepmc.org/abstract/MED/26765961

main subject

obesity

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metabolic dysfunction–associated steatotic liver disease

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based on heuristic

inferred from title

non-alcoholic fatty liver

1 reference

1

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10 June 2020

Xin Gao

15

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10 June 2020

author name string

Y Ling

2

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10 June 2020

H Bian

3

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10 June 2020

H-D Lin

4

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10 June 2020

H-M Yan

5

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10 June 2020

X-X Chang

6

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10 June 2020

X-M Li

7

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10 June 2020

H Ma

8

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10 June 2020

D Wang

9

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10 June 2020

L-S Zhang

10

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10 June 2020

S-S Wang

11

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10 June 2020

B-J Wu

12

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10 June 2020

W-Y He

13

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10 June 2020

N-Q Zhao

14

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10 June 2020

language of work or name

English

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publication date

13 January 2016

1 reference

28 February 2018

http://europepmc.org/abstract/MED/26765961

published in

Alimentary Pharmacology & Therapeutics

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26765961%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

43

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10 June 2020

issue

5

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10 June 2020

page(s)

631-642

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The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

10 June 2020

cites work

1 reference

Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008.

21 January 2018

1 reference

Non-alcoholic fatty liver disease: the mist gradually clears

21 January 2018

1 reference

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

21 January 2018

1 reference

Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease

21 January 2018

1 reference

Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): a population based study

21 January 2018

1 reference

Prevalence and risk factors of nonalcoholic fatty liver disease in an adult population of taiwan: metabolic significance of nonalcoholic fatty liver disease in nonobese adults.

21 January 2018

1 reference

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

21 January 2018

1 reference

Circulating triacylglycerol signatures and insulin sensitivity in NAFLD associated with the E167K variant in TM6SF2

21 January 2018

1 reference

Heritability of nonalcoholic fatty liver disease

21 January 2018

1 reference

Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits

21 January 2018

1 reference

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

21 January 2018

1 reference

Human fatty liver disease: old questions and new insights

21 January 2018

1 reference

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

21 January 2018

1 reference

Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity

21 January 2018

1 reference

Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption

21 January 2018

1 reference

Genetic variation in PNPLA3 (adiponutrin) confers sensitivity to weight loss-induced decrease in liver fat in humans

21 January 2018

1 reference

Standardized ultrasound hepatic/renal ratio and hepatic attenuation rate to quantify liver fat content: an improvement method

21 January 2018

1 reference

Assessment of liver fat content using quantitative ultrasonography to evaluate risks for metabolic diseases.

21 January 2018

1 reference

Liver fat content is associated with increased carotid atherosclerosis in a Chinese middle-aged and elderly population: the Shanghai Changfeng study

21 January 2018

1 reference

Liver fat content, evaluated through semi-quantitative ultrasound measurement, is associated with impaired glucose profiles: a community-based study in Chinese

21 January 2018

1 reference

Metabolic syndrome--a new world-wide definition. A Consensus Statement from the International Diabetes Federation

21 January 2018

1 reference

Comparative diagnostic accuracy of magnetic resonance elastography vs. eight clinical prediction rules for non-invasive diagnosis of advanced fibrosis in biopsy-proven non-alcoholic fatty liver disease: a prospective study.

21 January 2018

1 reference

Review article: Non-alcoholic fatty liver disease in morbidly obese patients and the effect of bariatric surgery

21 January 2018

1 reference

Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease

21 January 2018

1 reference

Magnetic resonance imaging and spectroscopy accurately estimate the severity of steatosis provided the stage of fibrosis is considered.

21 January 2018

1 reference

Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD

21 January 2018

1 reference

Association between novel MRI-estimated pancreatic fat and liver histology-determined steatosis and fibrosis in non-alcoholic fatty liver disease

21 January 2018

1 reference

Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods.

21 January 2018

1 reference

Controlled attenuation parameter (CAP): a novel VCTE™ guided ultrasonic attenuation measurement for the evaluation of hepatic steatosis: preliminary study and validation in a cohort of patients with chronic liver disease from various causes.

21 January 2018

1 reference

Noninvasive Diagnosis of Nonalcoholic Fatty Liver Disease and Quantification of Liver Fat Using a New Quantitative Ultrasound Technique

21 January 2018

1 reference

Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis

21 January 2018

1 reference

A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis

21 January 2018

1 reference

Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function

21 January 2018

1 reference

Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome

21 January 2018

1 reference

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

21 January 2018

1 reference

Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis

21 January 2018

1 reference

PNPLA3 rs738409 I748M is associated with steatohepatitis in 434 non-obese subjects with hepatitis C.

21 January 2018

1 reference

The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: a meta-analysis

21 January 2018

1 reference

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

21 January 2018

1 reference

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene

21 January 2018

1 reference

Long-term follow-up of patients with NAFLD and elevated liver enzymes

21 January 2018

1 reference

PNPLA3 GG genotype and carotid atherosclerosis in patients with non-alcoholic fatty liver disease

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/APT.13521

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26765961%20AND%20SRC:MED&resulttype=core&format=json

release_mi4e26quuzbilmxfwsbxj6xzsq

10 June 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/mi4e26quuzbilmxfwsbxj6xzsq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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