Identification of the Tau phosphorylation pattern that drives its aggregation. (Q50258556)

28 February 2018

title

Identification of the Tau phosphorylation pattern that drives its aggregation. (English)

1 reference

28 February 2018

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11

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28 February 2018

Isabelle Huvent

Isabelle Huvent

5

0 references

Yves Jacquot

Yves Jacquot

8

0 references

Isabelle Landrieu

9

Isabelle Landrieu

1 reference

28 February 2018

Guy Lippens

10

Guy Lippens

1 reference

28 February 2018

François-Xavier Cantrelle

4

François-Xavier Cantrelle

1 reference

28 February 2018

Étienne-Émile Baulieu

7

Etienne-Emile Baulieu

1 reference

28 February 2018

author name string

Clément Despres

1

1 reference

28 February 2018

Cillian Byrne

2

1 reference

28 February 2018

Haoling Qi

3

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28 February 2018

Béatrice Chambraud

6

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28 February 2018

language of work or name

English

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publication date

7 August 2017

1 reference

28 February 2018

Proceedings of the National Academy of Sciences of the United States of America

number of pages

6

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based on heuristic

inferred from page(s)

published in

1 reference

28 February 2018

volume

114

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28 February 2018

issue

34

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28 February 2018

page(s)

9080-9085

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28 February 2018

Unique pathological tau conformers from Alzheimer's brains transmit tau pathology in nontransgenic mice

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Oligomer formation of tau protein hyperphosphorylated in cells

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Conformational features of tau fibrils from Alzheimer's disease brain are faithfully propagated by unmodified recombinant protein

22 May 2018

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Brain homogenates from human tauopathies induce tau inclusions in mouse brain

22 May 2018

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22 May 2018

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Systematic identification of tubulin-interacting fragments of the microtubule-associated protein Tau leads to a highly efficient promoter of microtubule assembly

22 May 2018

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Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation

22 May 2018

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Tau-directed drug discovery for Alzheimer's disease and related tauopathies: a focus on tau assembly inhibitors

22 May 2018

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Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

22 May 2018

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Development of tau aggregation inhibitors for Alzheimer's disease

22 May 2018

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Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry

22 May 2018

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Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins

22 May 2018

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Tau polymerization: role of the amino terminus

22 May 2018

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Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments

22 May 2018

1 reference

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Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

22 May 2018

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Rapid assembly of Alzheimer-like paired helical filaments from microtubule-associated protein tau monitored by fluorescence in solution

22 May 2018

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Selective inhibition of Alzheimer disease-like tau aggregation by phenothiazines

22 May 2018

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

22 May 2018

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The purification of tau protein and the occurrence of two phosphorylation states of tau in brain

22 May 2018

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Phosphorylation of tau proteins to a state like that in Alzheimer's brain is catalyzed by a calcium/calmodulin-dependent kinase and modulated by phospholipids.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

22 May 2018

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Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.

22 May 2018

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The repeat region of microtubule-associated protein tau forms part of the core of the paired helical filament of Alzheimer's disease

22 May 2018

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Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

22 May 2018

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Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

22 May 2018

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Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro

22 May 2018

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The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

22 May 2018

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Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer's mice.

22 May 2018

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Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice

14 August 2018

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A Phosphorylation-Induced Turn Defines the Alzheimer's Disease AT8 Antibody Epitope on the Tau Protein.

14 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Conformation determines the seeding potencies of native and recombinant Tau aggregates

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Amplification of Tau fibrils from minute quantities of seeds

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Oleuropein and derivatives from olives as Tau aggregation inhibitors.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Epitope mapping of mAbs AT8 and Tau5 directed against hyperphosphorylated regions of the human tau protein

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Regions of tau implicated in the paired helical fragment core as defined by NMR.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Paired Helical Filaments in Electron Microscopy of Alzheimer's Disease

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

High-resolution magic angle spinning NMR of the neuronal tau protein integrated in Alzheimer's-like paired helical fragments

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576827

Mechanism of Tau-Promoted Microtubule Assembly As Probed by NMR Spectroscopy

2 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1708448114

Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28784767

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phosphorylation of tau protein by recombinant GSK-3beta: pronounced phosphorylation at select Ser/Thr-Pro motifs but no phosphorylation at Ser262 in the repeat domain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28784767

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1708448114

1 reference

28 February 2018

PMC publication ID

5576827

1 reference

28 February 2018

PubMed publication ID

28784767

1 reference

28 February 2018