Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge. (Q50479270)

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scientific article published on 6 June 2013

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English	Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge.	scientific article published on 6 June 2013

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scholarly article

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

Epigenetic induction of the Ink4a/Arf locus prevents Schwann cell overproliferation during nerve regeneration and after tumorigenic challenge. (English)

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

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Jose A Gomez-Sanchez

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

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Hugo Cabedo

7

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Clara Gomis-Coloma

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

Cruz Morenilla-Palao

3

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

Gloria Peiro

4

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

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publication date

6 June 2013

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

136

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

Pt 7

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http://europepmc.org/abstract/MED/23748155

2262-2278

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Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

1 reference

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21 January 2018

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

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AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regeneration

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

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Cell cycle inhibitors p21 and p16 are required for the regulation of Schwann cell proliferation.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

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Tissue repair and stem cell renewal in carcinogenesis

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WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway

1 reference

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Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve

1 reference

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How does the Schwann cell lineage form tumors in NF1?

1 reference

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Mouse models of tumor development in neurofibromatosis type 1

1 reference

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Senescence in tumours: evidence from mice and humans

1 reference

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Cellular senescence in cancer and aging

1 reference

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A negative feedback signaling network underlies oncogene-induced senescence

1 reference

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

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Malignant peripheral nerve sheath tumours in neurofibromatosis 1

1 reference

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Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Sustained axon-glial signaling induces Schwann cell hyperproliferation, Remak bundle myelination, and tumorigenesis.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Oncogene-induced senescence: the bright and dark side of the response

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Microanatomy of axon/glial signaling during Wallerian degeneration

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

In vivo detection of Egr2 binding to target genes during peripheral nerve myelination

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

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The origin and development of glial cells in peripheral nerves

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

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Negative regulation of myelination: relevance for development, injury, and demyelinating disease

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

A developmentally regulated switch directs regenerative growth of Schwann cells through cyclin D1.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

The essence of senescence

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

The Arf/p53 pathway in cancer and aging

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Schwann cell dedifferentiation is independent of mitogenic signaling and uncoupled to proliferation: role of cAMP and JNK in the maintenance of the differentiated state

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

A central role for the ERK-signaling pathway in controlling Schwann cell plasticity and peripheral nerve regeneration in vivo.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

c-Jun is a negative regulator of myelination.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Neurofibroma development in NF1--insights into tumour initiation

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Transforming growth factors-beta 1 and beta 2 are mitogens for rat Schwann cells

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Schwann cells express NDF and SMDF/n-ARIA mRNAs, secrete neuregulin, and show constitutive activation of erbB3 receptors: evidence for a neuregulin autocrine loop

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Studies of Schwann cell proliferation. I. An analysis in tissue culture of proliferation during development, Wallerian degeneration, and direct injury

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Studies of Schwann cell proliferation. III. Evidence for the surface localization of the neurite mitogen.

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT130

21 January 2018

Mechanisms of axon ensheathment and myelin growth

1 reference

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Measurement and comparison of serum neuregulin 1 immunoreactivity in control subjects and patients with schizophrenia: an influence of its genetic polymorphism.

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Mouse tumor model for neurofibromatosis type 1

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Heregulin beta1 promotes breast cancer cell proliferation through Rac/ERK-dependent induction of cyclin D1 and p21Cip1.

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21 January 2018

Identifiers

10.1093/BRAIN/AWT130

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

1 reference

Europe PubMed Central

14 March 2018

http://europepmc.org/abstract/MED/23748155

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