WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway (Q24324021)

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13 February 2020

title

WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway (English)

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13 February 2020

1 reference

GOA release 2020-03-11

tumor protein p53

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oxidative stress-induced premature senescence

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Manuel Collado

4

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13 February 2020

Manuel Serrano

9

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13 February 2020

Rémy Pedeux

11

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13 February 2020

author name string

Romuald Binet

1

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13 February 2020

Damien Ythier

2

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13 February 2020

Ana I Robles

3

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13 February 2020

Delphine Larrieu

5

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13 February 2020

Claire Fonti

6

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13 February 2020

Christian Brambilla

8

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13 February 2020

Curtis C Harris

10

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13 February 2020

Elisabeth Brambilla

7

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13 February 2020

language of work or name

English

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publication date

1 December 2009

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13 February 2020

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13 February 2020

volume

69

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13 February 2020

issue

24

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13 February 2020

page(s)

9183-9191

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Induction of cellular senescence by insulin-like growth factor binding protein-5 through a p53-dependent mechanism

13 February 2020

cites work

1 reference

12 December 2020

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

12 December 2020

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

1 reference

12 December 2020

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

1 reference

12 December 2020

Smurf2 up-regulation activates telomere-dependent senescence

1 reference

12 December 2020

Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis

1 reference

12 December 2020

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

1 reference

12 December 2020

The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells

1 reference

12 December 2020

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

1 reference

12 December 2020

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

1 reference

12 December 2020

Living on a break: cellular senescence as a DNA-damage response

1 reference

12 December 2020

Wnt5a and PKC, a deadly partnership involved in melanoma invasion.

1 reference

12 December 2020

The Wnt signaling pathway: aging gracefully as a protectionist?

1 reference

12 December 2020

Extension of life-span by introduction of telomerase into normal human cells

1 reference

12 December 2020

Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.

1 reference

12 December 2020

WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer.

1 reference

12 December 2020

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

1 reference

12 December 2020

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

1 reference

12 December 2020

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

12 December 2020

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

1 reference

12 December 2020

Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved

1 reference

12 December 2020

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence

1 reference

12 December 2020

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

1 reference

12 December 2020

ING2 controls the progression of DNA replication forks to maintain genome stability

1 reference

12 December 2020

Role for WNT16B in human epidermal keratinocyte proliferation and differentiation

1 reference

12 December 2020

Chemokine signaling via the CXCR2 receptor reinforces senescence

1 reference

12 December 2020

Telomere dysfunction and tumour suppression: the senescence connection

1 reference

12 December 2020

ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation

1 reference

12 December 2020

Augmented Wnt signaling in a mammalian model of accelerated aging

1 reference

12 December 2020

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

1 reference

12 December 2020

Tumour biology: senescence in premalignant tumours

1 reference

12 December 2020

WNT10B functional dualism: beta-catenin/Tcf-dependent growth promotion or independent suppression with deregulated expression in cancer

1 reference

12 December 2020

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

12 December 2020

The Wnt signaling pathway in development and disease

1 reference

12 December 2020

Wnt signaling in disease and in development

1 reference

12 December 2020

Methods to detect biomarkers of cellular senescence: the senescence-associated beta-galactosidase assay

1 reference

12 December 2020

Wnt-16a, a novel Wnt-16 isoform, which shows differential expression in adult human tissues

1 reference

12 December 2020

Mechanisms of cellular senescence in human and mouse cells.

1 reference

12 December 2020

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

12 December 2020

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

1 reference

12 December 2020

Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells

1 reference

12 December 2020

Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

1 reference

12 December 2020

10.1158/0008-5472.CAN-09-1016

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19951988%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

PMC publication ID

7439003

0 references

2 references

Consolidated OpenCitations Corpus – April 2017