α5 β1-integrins are sensors for tauroursodeoxycholic acid in hepatocytes. (Q50492543)

14 March 2018

title

α5 β1-integrins are sensors for tauroursodeoxycholic acid in hepatocytes. (English)

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5

Dieter Häussinger

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author name string

Holger Gohlke

1

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14 March 2018

Birte Schmitz

2

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Annika Sommerfeld

3

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Roland Reinehr

4

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language of work or name

English

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publication date

17 September 2012

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14 March 2018

published in

Hepatology

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volume

57

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issue

3

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page(s)

1117-1129

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A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. UDCA-PBC Study Group

cites work

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Cell volume and bile acid excretion

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Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner

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Hepatoprotection by hydrophilic bile salts

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Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver

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Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis

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Involvement of microtubules in the swelling-induced stimulation of transcellular taurocholate transport in perfused rat liver

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Involvement of integrins in osmosensing and signaling toward autophagic proteolysis in rat liver

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Involvement of integrins and Src in insulin signaling toward autophagic proteolysis in rat liver

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Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity

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Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

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Integrin activation dynamics between the RGD-binding site and the headpiece hinge

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The use of perfusion of liver and other organs for the study of microsomal electron-transport and cytochrome P-450 systems

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Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells

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Protein kinase C-dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells

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Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system

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Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis

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c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

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Insulin induces swelling-dependent activation of the epidermal growth factor receptor in rat liver

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Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

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A novel adaptation of the integrin PSI domain revealed from its crystal structure

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Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis

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Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver.

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Tauroursodeoxycholic acid exerts anticholestatic effects by a cooperative cPKC alpha-/PKA-dependent mechanism in rat liver.

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Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement

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7 January 2021

Ursodeoxycholic acid for treatment of primary sclerosing cholangitis: a placebo-controlled trial

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7 January 2021

Ursodeoxycholic acid in primary biliary cirrhosis: results of a controlled double-blind trial

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7 January 2021

Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver

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7 January 2021

Effect of S-adenosylmethionine versus tauroursodeoxycholic acid on bile acid-induced apoptosis and cytolysis in rat hepatocytes

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Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane

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Regulation of cell volume in the perfused rat liver by hormones

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Identifiers

DOI

10.1002/HEP.25992

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14 March 2018

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14 March 2018