Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression. (Q50660324)

17 March 2018

title

Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression. (English)

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17 March 2018

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11

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17 March 2018

Robert G. Bristow

12

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17 March 2018

Shane M Harding

object named as

S Harding

5

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Razq Hakem

object named as

R Hakem

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author name string

S El Ghamrasni

1

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17 March 2018

R Cardoso

2

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17 March 2018

M J Halaby

3

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17 March 2018

D Zeegers

4

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17 March 2018

R Kumareswaran

6

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17 March 2018

T Yavorska

7

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17 March 2018

N Chami

8

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17 March 2018

A Jurisicova

9

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17 March 2018

O Sanchez

10

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17 March 2018

A Hakem

14

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17 March 2018

language of work or name

English

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publication date

26 May 2014

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17 March 2018

published in

Oncogene

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17 March 2018

volume

34

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17 March 2018

issue

14

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17 March 2018

page(s)

1780-1789

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17 March 2018

https://scigraph.springernature.com/pub.10.1038/onc.2014.121

exact match

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cites work

DNA double-strand break signaling and human disorders

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https://api.crossref.org/works/10.1038%2FONC.2014.121

RecQ helicases: multifunctional genome caretakers

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.121

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.121

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

21 January 2018

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BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

SUMO modification regulates BLM and RAD51 interaction at damaged replication forks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Structural and functional relationships of the XPF/MUS81 family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

BLM helicase facilitates Mus81 endonuclease activity in human cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.121

Involvement of mammalian Mus81 in genome integrity and tumor suppression

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.121

Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis

21 January 2018

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Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Decreased expression of methyl methansulfonate and ultraviolet-sensitive gene clone 81 (Mus81) is correlated with a poor prognosis in patients with hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Aberrant chromosome morphology in human cells defective for Holliday junction resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Human Mus81-associated endonuclease cleaves Holliday junctions in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Mechanisms of recombination between diverged sequences in wild-type and BLM-deficient mouse and human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Genetic interactions between BLM and DNA ligase IV in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Playing the end game: DNA double-strand break repair pathway choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Downregulation of Mus81 as a novel prognostic biomarker for patients with colorectal carcinoma.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.121

Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.121

Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.121

DNA interstrand crosslink repair and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Mutation of the murine Bloom's syndrome gene produces global genome destabilization

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.121

Mus81-Eme1 are essential components of a Holliday junction resolvase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

RecQ helicase, Sgs1, and XPF family endonuclease, Mus81-Mms4, resolve aberrant joint molecules during meiotic recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

BLM helicase ortholog Sgs1 is a central regulator of meiotic recombination intermediate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Sgs1--the maestro of recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Human Rad54 protein stimulates human Mus81-Eme1 endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

MUS81 promotes common fragile site expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Methods for studying the cellular response to DNA damage: influence of the Mre11 complex on chromosome metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Expression and functional analysis of AtMUS81 in Arabidopsis meiosis reveals a role in the second pathway of crossing-over

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Functional Interplay of p53 and Mus81 in DNA Damage Responses and Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.121

The Mus81/Mms4 Endonuclease Acts Independently of Double-Holliday Junction Resolution to Promote a Distinct Subset of Crossovers During Meiosis in Budding Yeast

31 March 2020

1 reference

12 December 2020

Expression and functional analysis of AtMUS81 in Arabidopsis meiosis reveals a role in the second pathway of crossing-over

1 reference

12 December 2020

Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae

1 reference

12 December 2020

A role for MMS4 in the processing of recombination intermediates during meiosis in Saccharomyces cerevisiae

1 reference

12 December 2020

Down-regulation of Mus81 as a potential marker for the malignancy of gastric cancer.

1 reference

12 December 2020

Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversion

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2014.121

1 reference

17 March 2018

1 reference

17 March 2018