NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. (Q50878030)

24 March 2018

title

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. (English)

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24 March 2018

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Wei Zou

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Steven L. Teitelbaum

8

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Chin-Tong Ong

object named as

Chin-tong Ong

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Matthew J Hilton

object named as

Matthew J Hilton

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author name string

Shuting Bai

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24 March 2018

Fanxin Long

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F Patrick Ross

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language of work or name

English

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publication date

22 December 2007

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Journal of Biological Chemistry

published in

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volume

283

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issue

10

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24 March 2018

page(s)

6509-6518

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24 March 2018

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

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Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes.

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Notch signaling in mammary development and oncogenesis

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Learning and memory deficits in Notch mutant mice.

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

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Immunology. Keeping a tight leash on Notch.

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Notch signaling as a therapeutic target

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Notch1 functions as a tumor suppressor in mouse skin

21 January 2018

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DNER acts as a neuron-specific Notch ligand during Bergmann glial development

21 January 2018

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F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation

21 January 2018

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Structural basis for autoinhibition of Notch

21 January 2018

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Hey genes in cardiovascular development

21 January 2018

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HES and HERP families: multiple effectors of the Notch signaling pathway

21 January 2018

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The long and short of it: somite formation in mice

21 January 2018

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Skeletal and CNS defects in Presenilin-1-deficient mice

21 January 2018

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Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

21 January 2018

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Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis

21 January 2018

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Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity

21 January 2018

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Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells

21 January 2018

1 reference

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Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling

21 January 2018

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Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling

21 January 2018

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Osteoclasts: what do they do and how do they do it?

21 January 2018

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M-CSF mediates TNF-induced inflammatory osteolysis

21 January 2018

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gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis

21 January 2018

1 reference

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Osteoblast-derived PTHrP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34.

21 January 2018

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Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts

21 January 2018

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The HIV protease inhibitor ritonavir blocks osteoclastogenesis and function by impairing RANKL-induced signaling

21 January 2018

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Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

21 January 2018

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Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

21 January 2018

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Notch1 is essential for postimplantation development in mice.

21 January 2018

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Anchoring notch genetics and biochemistry; structural analysis of the ankyrin domain sheds light on existing data

21 January 2018

1 reference

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Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity

21 January 2018

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The Notch ligand, Delta-1, inhibits the differentiation of monocytes into macrophages but permits their differentiation into dendritic cells.

21 January 2018

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Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

21 January 2018

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Notch signalling controls pancreatic cell differentiation

21 January 2018

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Osteoblastic cells regulate the haematopoietic stem cell niche

21 January 2018

1 reference

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Parathyroid hormone stimulates expression of the Notch ligand Jagged1 in osteoblastic cells.

21 January 2018

1 reference

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Notch signaling in development and cancer.

21 January 2018

1 reference

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Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707000200

21 January 2018

Identifiers

DOI

10.1074/JBC.M707000200

1 reference

24 March 2018

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24 March 2018