IL-2 promotes the function of memory-like autoregulatory CD8+ T cells but suppresses their development via FoxP3+ Treg cells. (Q50927181)

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18 February 2020

title

IL-2 promotes the function of memory-like autoregulatory CD8+ T cells but suppresses their development via FoxP3+ Treg cells (English)

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18 February 2020

6

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18 February 2020

author name string

Afshin Shameli

1

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18 February 2020

Jun Yamanouchi

2

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18 February 2020

Sue Tsai

3

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18 February 2020

Yang Yang

4

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18 February 2020

Xavier Clemente-Casares

5

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18 February 2020

Pau Serra

7

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18 February 2020

Pere Santamaria

8

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18 February 2020

language of work or name

English

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publication date

15 January 2013

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European Journal of Immunology

18 February 2020

published in

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18 February 2020

volume

43

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18 February 2020

page(s)

394-403

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18 February 2020

issue

2

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T-cell autoantigens in the non-obese diabetic mouse model of autoimmune diabetes

18 February 2020

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Reversal of autoimmunity by boosting memory-like autoregulatory T cells

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IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion

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Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

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IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

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Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction

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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

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Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms

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Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

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CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells.

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Development of memory-like autoregulatory CD8+ T cells is CD4+ T cell dependent.

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Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells

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Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells.

21 January 2018

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Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

21 January 2018

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CD4+CD25+ regulatory T cells suppress allograft rejection mediated by memory CD8+ T cells via a CD30-dependent mechanism

21 January 2018

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Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses

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Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C

21 January 2018

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CD25+CD4+ T cells contribute to the control of memory CD8+ T cells

21 January 2018

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CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses

21 January 2018

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IL-2 regulates perforin and granzyme gene expression in CD8+ T cells independently of its effects on survival and proliferation.

21 January 2018

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Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13.

21 January 2018

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Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)-T-cell-deficient mice

21 January 2018

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CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

21 January 2018

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Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

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21 January 2018

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7 January 2021

Immunostimulation circumvents diabetes in NOD/Lt mice

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7 January 2021

The dual role of IL-2 in the generation and maintenance of CD8+ memory T cells

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7 January 2021

A novel galectin-1 and interleukin 2 receptor β haplotype is associated with autoimmune myasthenia gravis

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7 January 2021

Identifiers

DOI

10.1002/EJI.201242845

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23180662%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

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