Orphan nuclear receptor Nur77 promotes colorectal cancer invasion and metastasis by regulating MMP-9 and E-cadherin. (Q51066152)

28 March 2018

title

Orphan nuclear receptor Nur77 promotes colorectal cancer invasion and metastasis by regulating MMP-9 and E-cadherin. (English)

1 reference

28 March 2018

1 reference

1 reference

1 reference

Jing-Ru Wang

1

1 reference

28 March 2018

Wen-Juan Gan

2

1 reference

28 March 2018

Xiu-Ming Li

3

1 reference

28 March 2018

Yuan-Yuan Zhao

4

1 reference

28 March 2018

Ying Li

5

1 reference

28 March 2018

Xing-Xing Lu

6

1 reference

28 March 2018

Jian-Ming Li

7

1 reference

28 March 2018

Hua Wu

8

1 reference

28 March 2018

language of work or name

English

0 references

publication date

26 July 2014

1 reference

28 March 2018

published in

Carcinogenesis

1 reference

28 March 2018

volume

35

1 reference

28 March 2018

issue

11

1 reference

28 March 2018

page(s)

2474-2484

1 reference

28 March 2018

Molecular events in primary and metastatic colorectal carcinoma: a review

cites work

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Dissecting the metastatic cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Molecular mechanisms of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

A causal role for E-cadherin in the transition from adenoma to carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Mutations of the human E-cadherin (CDH1) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Twist is a transcriptional repressor of E-cadherin gene expression in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Matrix metalloproteinases and tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

EGF-induced MMP-9 expression is mediated by the JAK3/ERK pathway, but not by the JAK3/STAT-3 pathway in a SKBR3 breast cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

TNF-alpha induces MMP-9 expression via activation of Src/EGFR, PDGFR/PI3K/Akt cascade and promotion of NF-kappaB/p300 binding in human tracheal smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Targeting Nur77 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Targeting NR4A1 (TR3) in cancer cells and tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Dual roles of Nur77 in selective regulation of apoptosis and cell cycle by TPA and ATRA in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Activation of nerve growth factor-induced B alpha by methylene-substituted diindolylmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Hypoxia and hypoxia-inducible factors: master regulators of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Prostaglandin E2 increases growth and motility of colorectal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

A molecular signature of metastasis in primary solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

TR3 modulates platinum resistance in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Orphan receptor TR3 is essential for the maintenance of stem-like properties in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Orphan receptor TR3 participates in cisplatin-induced apoptosis via Chk2 phosphorylation to repress intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Downregulated E-cadherin expression indicates worse prognosis in Asian patients with colorectal cancer: evidence from meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Engagement of collagen-binding integrins promotes matrix metalloproteinase-9-dependent E-cadherin ectodomain shedding in ovarian carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Matrix metalloproteinase 9 is a mediator of epidermal growth factor-dependent e-cadherin loss in ovarian carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Hypoxia enhances colon cancer migration and invasion through promotion of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

A tumor hypoxic niche protects human colon cancer stem cells from chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Hypoxia triggers a Nur77-β-catenin feed-forward loop to promote the invasive growth of colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

Transcriptional repression of matrix metalloproteinase gene expression by the orphan nuclear receptor NURR1 in cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGU157

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGU157

1 reference

28 March 2018

1 reference

28 March 2018