Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3β/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia. (Q51161546)

31 March 2018

title

Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3β/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia. (English)

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31 March 2018

author name string

Xiaozhen Dai

1

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31 March 2018

Xiaoqing Yan

2

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31 March 2018

Jun Zeng

3

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31 March 2018

Jing Chen

4

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31 March 2018

Yuehui Wang

5

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31 March 2018

Jun Chen

6

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31 March 2018

Yan Li

7

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31 March 2018

Michelle T Barati

8

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31 March 2018

Kupper A Wintergerst

9

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31 March 2018

Kejian Pan

10

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31 March 2018

Matthew A Nystoriak

11

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31 March 2018

Daniel J Conklin

12

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31 March 2018

Gregg Rokosh

13

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31 March 2018

Paul N Epstein

14

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31 March 2018

Xiaokun Li

15

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31 March 2018

Yi Tan

16

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31 March 2018

publication date

30 January 2017

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31 March 2018

published in

Circulation Research

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31 March 2018

volume

120

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31 March 2018

page(s)

e7-e23

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31 March 2018

issue

5

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31 March 2018

Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration

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22 May 2018

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Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo

22 May 2018

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Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression

22 May 2018

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Adiponectin prevents diabetic premature senescence of endothelial progenitor cells and promotes endothelial repair by suppressing the p38 MAP kinase/p16INK4A signaling pathway.

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A novel CXCR4 antagonist derived from human SDF-1beta enhances angiogenesis in ischaemic mice

22 May 2018

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22 May 2018

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Significance of endothelial progenitor cells in subjects with diabetes.

22 May 2018

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Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia

22 May 2018

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Phosphorylation of tyrosine 568 controls nuclear export of Nrf2.

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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Up-regulation of Nrf2 is involved in FGF21-mediated fenofibrate protection against type 1 diabetic nephropathy.

22 May 2018

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Puerarin induces the upregulation of glutathione levels and nuclear translocation of Nrf2 through PI3K/Akt/GSK-3β signaling events in PC12 cells exposed to lead

14 August 2018

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CXCR7 participates in CXCL12-induced CD34+ cell cycling through β-arrestin-dependent Akt activation.

14 August 2018

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CXCR7 upregulation is required for early endothelial progenitor cell-mediated endothelial repair in patients with hypertension.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336396

Hyperglycemia and oxidized-LDL exert a deleterious effect on endothelial progenitor cell migration in type 2 diabetes mellitus

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336396

The chemokine SDF-1/CXCL12 contributes to the 'homing' of umbilical cord blood cells to a hypoxic-ischemic lesion in the rat brain.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336396

p66ShcA modulates oxidative stress and survival of endothelial progenitor cells in response to high glucose

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336396

Antioxidant therapy attenuates diabetes-related impairment of bone marrow stem cells

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336396

Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336396

Antioxidative stress-associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5336396

Chemokine receptor CXCR7 mediates human endothelial progenitor cells survival, angiogenesis, but not proliferation

14 August 2018

1 reference

12 December 2020

Nitric oxide activates Nrf2 through S-nitrosylation of Keap1 in PC12 cells

1 reference

12 December 2020

Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone

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12 December 2020

Rationale and design of Enhanced Angiogenic Cell Therapy in Acute Myocardial Infarction (ENACT-AMI): The first randomized placebo-controlled trial of enhanced progenitor cell therapy for acute myocardial infarction

1 reference

12 December 2020

A novel mechanism for endothelial progenitor cells homing: The SDF-1/CXCR4-Rac pathway may regulate endothelial progenitor cells homing through cellular polarization

1 reference

12 December 2020

10.1161/CIRCRESAHA.117.310619

Identifiers

DOI

1 reference

31 March 2018

PMCID

5336396

1 reference

31 March 2018

PubMed ID

28137917

1 reference

31 March 2018