Luteolin reduces obesity-associated insulin resistance in mice by activating AMPKα1 signalling in adipose tissue macrophages. (Q51268350)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27377644%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Luteolin reduces obesity-associated insulin resistance in mice by activating AMPKα1 signalling in adipose tissue macrophages (English)

1 reference

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17 March 2020

0 references

1 reference

7

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17 March 2020

author name string

Lei Zhang

1

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17 March 2020

Yi-Jing Han

2

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17 March 2020

Xian Zhang

3

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17 March 2020

Xin Wang

4

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17 March 2020

Bin Bao

5

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17 March 2020

Wei Qu

6

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17 March 2020

publication date

4 July 2016

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17 March 2020

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17 March 2020

volume

59

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17 March 2020

issue

10

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17 March 2020

page(s)

2219-2228

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Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity

17 March 2020

cites work

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Mast cells, macrophages, and crown-like structures distinguish subcutaneous from visceral fat in mice

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

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Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity

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Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes

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The role of innate immune cells in obese adipose tissue inflammation and development of insulin resistance.

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Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages

21 January 2018

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Low-dose diet supplement of a natural flavonoid, luteolin, ameliorates diet-induced obesity and insulin resistance in mice.

21 January 2018

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Luteolin inhibits inflammatory responses via p38/MK2/TTP-mediated mRNA stability.

21 January 2018

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Luteolin, a food-derived flavonoid, suppresses adipocyte-dependent activation of macrophages by inhibiting JNK activation.

21 January 2018

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Luteolin suppresses inflammation-associated gene expression by blocking NF-kappaB and AP-1 activation pathway in mouse alveolar macrophages

21 January 2018

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AMPK promotes macrophage fatty acid oxidative metabolism to mitigate inflammation: implications for diabetes and cardiovascular disease

21 January 2018

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AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

21 January 2018

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Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype

21 January 2018

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Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

21 January 2018

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Reduction of lipid accumulation in HepG2 cells by luteolin is associated with activation of AMPK and mitigation of oxidative stress

21 January 2018

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Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1.

21 January 2018

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Momordica charantia (Bitter Melon) reduces obesity-associated macrophage and mast cell infiltration as well as inflammatory cytokine expression in adipose tissues

21 January 2018

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Implication of the Tpl2 kinase in inflammatory changes and insulin resistance induced by the interaction between adipocytes and macrophages

21 January 2018

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CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice

21 January 2018

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Distribution and biological activities of the flavonoid luteolin

21 January 2018

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Luteolin ameliorates cardiac failure in type I diabetic cardiomyopathy.

21 January 2018

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Type 2 diabetes as an inflammatory disease

21 January 2018

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Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages

21 January 2018

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21 January 2018

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Unique proteomic signatures distinguish macrophages and dendritic cells

21 January 2018

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AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation.

21 January 2018

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AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

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Quercetin, luteolin, and epigallocatechin gallate promote glucose disposal in adipocytes with regulation of AMP-activated kinase and/or sirtuin 1 activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27377644

12 December 2020

inferred from PubMed ID database lookup

Luteolin and chrysin differentially inhibit cyclooxygenase-2 expression and scavenge reactive oxygen species but similarly inhibit prostaglandin-E2 formation in RAW 264.7 cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27377644

12 December 2020

inferred from PubMed ID database lookup

Protective Effects of Luteolin on Diabetic Nephropathy in STZ-Induced Diabetic Rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27377644

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S00125-016-4039-8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27377644%20AND%20SRC:MED&resulttype=core&format=json

release_tg3u6bqba5cmdar4frsfbd5bqy

17 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tg3u6bqba5cmdar4frsfbd5bqy

24 November 2022

mapped directly with Wikidata item

1 reference