Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes. (Q51905804)

http://europepmc.org/abstract/MED/20571128

17 April 2018

title

Nodal signaling recruits the histone demethylase Jmjd3 to counteract polycomb-mediated repression at target genes (English)

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13 May 2020

3

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13 May 2020

author name string

Øyvind Dahle

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6953396&resulttype=core&format=json

13 May 2020

Amit Kumar

series ordinal

2

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13 May 2020

publication date

22 June 2010

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http://europepmc.org/abstract/MED/20571128

17 April 2018

published in

Science Signaling

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volume

3

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issue

127

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page(s)

ra48

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Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

13 May 2020

cites work

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12 December 2020

Nodal signaling: developmental roles and regulation.

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12 December 2020

The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo

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12 December 2020

Genetics and epigenetics: stability and plasticity during cellular differentiation

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12 December 2020

Nodal Signaling in Vertebrate Development

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12 December 2020

Asymmetric Nodal expression in the mouse is governed by the combinatorial activities of two distinct regulatory elements.

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12 December 2020

The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4.

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12 December 2020

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

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12 December 2020

Derivation of pluripotent epiblast stem cells from mammalian embryos

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12 December 2020

Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression

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12 December 2020

Biochemical mechanisms of gene regulation by polycomb group protein complexes

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12 December 2020

Smad transcription factors

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12 December 2020

Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2

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12 December 2020

Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells

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12 December 2020

Polycomb/Trithorax response elements and epigenetic memory of cell identity

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12 December 2020

Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer

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12 December 2020

rVISTA 2.0: evolutionary analysis of transcription factor binding sites

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12 December 2020

Mechanisms of polycomb gene silencing: knowns and unknowns

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12 December 2020

Epigenetic regulation of the alternatively activated macrophage phenotype

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12 December 2020

Mechanisms involved in the regulation of histone lysine demethylases

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12 December 2020

New cell lines from mouse epiblast share defining features with human embryonic stem cells

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12 December 2020

Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice

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12 December 2020

Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

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12 December 2020

Asymmetric and node-specific nodal expression patterns are controlled by two distinct cis-acting regulatory elements

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12 December 2020

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

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12 December 2020

The key to left-right asymmetry

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12 December 2020

The emerging functions of histone demethylases

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12 December 2020

Polycomb group proteins: navigators of lineage pathways led astray in cancer

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12 December 2020

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

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12 December 2020

Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

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12 December 2020

Cell fate decisions within the mouse organizer are governed by graded Nodal signals

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12 December 2020

Defining an epigenetic code

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12 December 2020

Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

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12 December 2020

Developmental roles of the histone lysine demethylases

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12 December 2020

Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads

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12 December 2020

The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

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12 December 2020

The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse

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12 December 2020

The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment

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12 December 2020

Chromatin immunoprecipitation and microarray-based analysis of protein location

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12 December 2020

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

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12 December 2020

Two nodal-responsive enhancers control left-right asymmetric expression of Nodal.

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12 December 2020

Transcription factors, chromatin and cancer

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12 December 2020

Combinatorial activities of Smad2 and Smad3 regulate mesoderm formation and patterning in the mouse embryo

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12 December 2020

Polycomb complexes and epigenetic states

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12 December 2020

The polycomb group protein Suz12 is required for embryonic stem cell differentiation

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12 December 2020

An essential interaction between T-box proteins and histone-modifying enzymes

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12 December 2020

10.1126/SCISIGNAL.2000841

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6953396&resulttype=core&format=json

13 May 2020

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13 May 2020

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