Overexpression of activated neu/erbB2 initiates immortalization and malignant transformation of immature Schwann cells in vitro. (Q52172506)

26 April 2018

title

Overexpression of activated neu/erbB2 initiates immortalization and malignant transformation of immature Schwann cells in vitro. (English)

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26 April 2018

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Sherman L

1

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26 April 2018

Sleeman JP

2

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26 April 2018

Hennigan RF

3

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26 April 2018

Herrlich P

4

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26 April 2018

Ratner N

5

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26 April 2018

language of work or name

English

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publication date

1 November 1999

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26 April 2018

published in

Oncogene

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26 April 2018

volume

18

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26 April 2018

issue

48

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26 April 2018

page(s)

6692-6699

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26 April 2018

The molecular genetics of cancer

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Expression of the neu proto-oncogene by Schwann cells during peripheral nerve development and Wallerian degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin A in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Extended life span and tumorigenicity of nonestablished mouse connective tissue cells transformed by the fos oncogene of FBR-MuSV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Involvement of pp60c-src with two major signaling pathways in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Glial growth factors are alternatively spliced erbB2 ligands expressed in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Towards an understanding of the malignant transformation of diploid human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Cell immortalization as a key, rate-limiting event in malignant transformation: approaches toward a molecular genetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Early mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Development of a monoclonal antibody against a tumor-associated antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosourea

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Studies of Schwann cell proliferation. I. An analysis in tissue culture of proliferation during development, Wallerian degeneration, and direct injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Clonal cell lines from the rat central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Constitutive activation of delayed-rectifier potassium channels by a src family tyrosine kinase in Schwann cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

In vitro segregation of different cell lines with neuronal and glial properties from a stem cell line of rat neurotumor RT4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Irreversible inhibition of v-src tyrosine kinase activity by herbimycin A and its abrogation by sulfhydryl compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Axonal neuregulin signals cells of the oligodendrocyte lineage through activation of HER4 and Schwann cells through HER2 and HER3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

The multistep nature of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Intermolecular association of the p185neu protein and EGF receptor modulates EGF receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

Transformation of NIH 3T3 cells by overexpression of the normal coding sequence of the rat neu gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

[Cancerogenic effects of methyl- and ethyl-nitrosourea (MNU and ENU) at single intracerebral and intracarotidal injection in newborn and young BD-rats]

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

Axonal interactions regulate Schwann cell apoptosis in developing peripheral nerve: neuregulin receptors and the role of neuregulins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

The biology of erbB-2/neu/HER-2 and its role in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

cAMP-dependent protein kinase A is required for Schwann cell growth: interactions between the cAMP and neuregulin/tyrosine kinase pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

The influence of heregulins on human Schwann cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

Structural modifications and repair of DNA in neuro-oncogenesis by N-ethyl-N-nitrosourea

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

Interdomain binding mediates tumor growth suppression by the NF2 gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

Molecular and clinical aspects of the Neu/ErbB-2 receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

The ErbB-2/HER2 oncogenic receptor of adenocarcinomas: from orphanhood to multiple stromal ligands

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203055

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203055

1 reference

26 April 2018

1 reference

26 April 2018