Mutations of the AML1 gene in acute myeloid leukemia of FAB types M0 and M7. (Q52545702)

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8 December 2019

title

Mutations of the AML1 gene in acute myeloid leukemia of FAB types M0 and M7 (English)

1 reference

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8 December 2019

main subject

acute myeloid leukemia

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1

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8 December 2019

Gareth J Morgan

series ordinal

4

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8 December 2019

5

David C Linch

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8 December 2019

2

Rosemary E Gale

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8 December 2019

author name string

Sara J Rollinson

series ordinal

3

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8 December 2019

publication date

1 May 2002

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Genes, Chromosomes and Cancer

8 December 2019

published in

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8 December 2019

volume

34

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8 December 2019

issue

1

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8 December 2019

page(s)

24-32

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Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7). A report of the French-American-British Cooperative Group

8 December 2019

cites work

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Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-MO)

21 January 2018

1 reference

The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains

21 January 2018

1 reference

Secondary acute myeloblastic leukemia with t(16;21) (q24;q22). involving the AML1 gene

21 January 2018

1 reference

Biochemical and biophysical properties of the core-binding factor alpha2 (AML1) DNA-binding domain.

21 January 2018

1 reference

Leukaemia/Drosophila homology

21 January 2018

1 reference

The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance

21 January 2018

1 reference

Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

21 January 2018

1 reference

A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA binding ability and the transforming activity on fibroblasts

21 January 2018

1 reference

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

21 January 2018

1 reference

21 January 2018

Acute myeloid leukemia

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Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation

21 January 2018

1 reference

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

21 January 2018

1 reference

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

21 January 2018

1 reference

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

21 January 2018

1 reference

Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia

21 January 2018

1 reference

Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain

21 January 2018

1 reference

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells

21 January 2018

1 reference

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

1 reference

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

21 January 2018

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AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

21 January 2018

1 reference

Identification of two new translocations that disrupt the AML1 gene

21 January 2018

1 reference

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

1 reference

Biophysical characterization of interactions between the core binding factor alpha and beta subunits and DNA.

21 January 2018

1 reference

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

1 reference

Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta

21 January 2018

1 reference

The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

21 January 2018

1 reference

CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter

21 January 2018

1 reference

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice

21 January 2018

1 reference

Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1

21 January 2018

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Patients with t(8;21)(q22;q22) and acute myeloid leukemia have superior failure-free and overall survival when repetitive cycles of high-dose cytarabine are administered

21 January 2018

1 reference

Molecular diagnosis of haematological disorders using DNA from stored bone marrow slides

21 January 2018

1 reference

Cbfa1 in bone development

21 January 2018

1 reference

Trisomy 13 and myeloid malignancy--characteristic blast cell morphology: a United Kingdom Cancer Cytogenetics Group survey

21 January 2018

1 reference

Functional mutagenesis of AML1/RUNX1 and PEBP2 beta/CBF beta define distinct, non-overlapping sites for DNA recognition and heterodimerization by the Runt domain

21 January 2018

1 reference

Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties.

21 January 2018

1 reference

Redox regulation of the DNA binding activity in transcription factor PEBP2. The roles of two conserved cysteine residues

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/GCC.10031

1 reference

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8 December 2019

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