NKG2D-mediated cytotoxicity toward oligodendrocytes suggests a mechanism for tissue injury in multiple sclerosis. (Q52576677)

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25 December 2019

title

NKG2D-mediated cytotoxicity toward oligodendrocytes suggests a mechanism for tissue injury in multiple sclerosis (English)

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25 December 2019

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Philippe Saikali

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Jack P. Antel

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Zhihong Chen

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Alexandre Prat

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25 December 2019

author name string

Jia Newcombe

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Mark Freedman

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Manon Blain

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Romain Cayrol

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Jeffery A Hall

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language of work or name

English

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publication date

1 January 2007

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25 December 2019

published in

Journal of Neuroscience

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volume

27

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issue

5

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page(s)

1220-1228

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Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB

25 December 2019

cites work

1 reference

12 December 2020

MIC genes: from genetics to biology

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12 December 2020

CD4+,CD28- T cells in rheumatoid arthritis patients combine features of the innate and adaptive immune systems

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12 December 2020

Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells

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12 December 2020

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

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12 December 2020

Regulation of the natural killer cell receptor repertoire

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12 December 2020

NK cell-mediated lysis of autologous human oligodendrocytes

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12 December 2020

Ligands for natural killer cell receptors: redundancy or specificity

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12 December 2020

In vivo expression of major histocompatibility complex molecules on oligodendrocytes and neurons during viral infection

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12 December 2020

CD4+CD28- costimulation-independent T cells in multiple sclerosis

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12 December 2020

Binding of Escherichia coli adhesin AfaE to CD55 triggers cell-surface expression of the MHC class I-related molecule MICA

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12 December 2020

Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis

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12 December 2020

Identification of new therapeutic targets for prevention of CNS inflammation

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12 December 2020

Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity

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12 December 2020

Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid

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12 December 2020

Natural killer cell-mediated lysis of dorsal root ganglia neurons via RAE1/NKG2D interactions.

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12 December 2020

Selective intracellular retention of virally induced NKG2D ligands by the human cytomegalovirus UL16 glycoprotein

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12 December 2020

Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia

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12 December 2020

Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis

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12 December 2020

Gamma delta T-cell receptor repertoire in acute multiple sclerosis lesions

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12 December 2020

Roles of the NKG2D immunoreceptor and its ligands

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12 December 2020

Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors

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12 December 2020

NKG2D blockade prevents autoimmune diabetes in NOD mice

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12 December 2020

HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells

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12 December 2020

Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease

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12 December 2020

A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease.

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12 December 2020

Interleukin-1: a master regulator of neuroinflammation

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12 December 2020

Demyelination and inhibition of tumor necrosis factor (TNF).

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12 December 2020

Distinctive properties of human adult brain-derived myelin progenitor cells.

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12 December 2020

Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias

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12 December 2020

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12 December 2020

Immunology of multiple sclerosis

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12 December 2020

NKG2D is a costimulatory receptor for human naive CD8+ T cells.

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12 December 2020

LINGO-1 negatively regulates myelination by oligodendrocytes

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12 December 2020

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

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12 December 2020

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

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12 December 2020

Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirus

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12 December 2020

Activation of V gamma 9V delta 2 T cells by NKG2D.

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12 December 2020

TLR signaling tailors innate immune responses in human microglia and astrocytes

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12 December 2020

Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium

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12 December 2020

TNFalpha stimulates NKG2D-mediated lytic activity of acute myeloid leukemic cells

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12 December 2020

Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes

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12 December 2020

TGF-beta and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells

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12 December 2020

Peripheral blood ?-? T cells lyse fresh human brain?Derived oligodendrocytes

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12 December 2020

Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury.

1 reference

12 December 2020

Induction of MHC class I genes in neurons

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12 December 2020

Microglia-derived macrophages in early multiple sclerosis plaques

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12 December 2020

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium

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12 December 2020

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12 December 2020

MHC class I-restricted lysis of human oligodendrocytes by myelin basic protein peptide-specific CD8 T lymphocytes

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12 December 2020

Mechanism of gammadelta T cell-induced human oligodendrocyte cytotoxicity: relevance to multiple sclerosis

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12 December 2020

Cytokine actions in the central nervous system

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12 December 2020

10.1523/JNEUROSCI.4402-06.2007

Identifiers

DOI

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25 December 2019

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25 December 2019

PubMed publication ID

17267578

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