IL-19 is a component of the pathogenetic IL-23/IL-17 cascade in psoriasis. (Q52875207)

9 May 2018

http://europepmc.org/abstract/MED/25046339

title

IL-19 is a component of the pathogenetic IL-23/IL-17 cascade in psoriasis. (English)

1 reference

9 May 2018

http://europepmc.org/abstract/MED/25046339

author name string

Ellen Witte

1

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13 June 2020

Georgios Kokolakis

2

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13 June 2020

Katrin Witte

3

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13 June 2020

Sandra Philipp

4

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13 June 2020

Wolf-Dietrich Doecke

5

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13 June 2020

Bianca M Wittig

7

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13 June 2020

Katarzyna Warszawska

8

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13 June 2020

Agata Kurek

9

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13 June 2020

Magdalena Erdmann-Keding

10

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13 June 2020

Stefanie Kunz

11

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13 June 2020

Khusru Asadullah

12

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13 June 2020

Marshall E Kadin

13

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13 June 2020

Wolfram Sterry

15

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13 June 2020

Kerstin Wolk

16

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13 June 2020

Robert Sabat

17

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13 June 2020

language of work or name

English

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publication date

21 July 2014

1 reference

9 May 2018

http://europepmc.org/abstract/MED/25046339

published in

Journal of Investigative Dermatology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25046339%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

134

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25046339%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

11

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13 June 2020

page(s)

2757-2767

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Epidermal overexpression of interleukin-19 and -20 mRNA in psoriatic skin disappears after short-term treatment with cyclosporine a or calcipotriol.

13 June 2020

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Deficiency of IL-22 contributes to a chronic inflammatory disease: pathogenetic mechanisms in acne inversa.

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Protective role of interleukin-19 gene polymorphisms in patients with ulcerative colitis

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Interleukin 20: discovery, receptor identification, and role in epidermal function

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Inhibition of ERK MAPK Suppresses IL-23- and IL-1-Driven IL-17 Production and Attenuates Autoimmune Disease

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Association analysis of IL19, IL20 and IL24 genes in palmoplantar pustulosis.

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beta-Defensins chemoattract macrophages and mast cells but not lymphocytes and dendritic cells: CCR6 is not involved.

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IL-24 transgenic mice: in vivo evidence of overlapping functions for IL-20, IL-22, and IL-24 in the epidermis

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Endogenous antimicrobial peptides and skin infections in atopic dermatitis

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IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells

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IL-19 is involved in the pathogenesis of endotoxic shock

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12 December 2020

Expression and suppressive effects of interleukin-19 on vascular smooth muscle cell pathophysiology and development of intimal hyperplasia

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12 December 2020

The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury

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12 December 2020

Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types

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12 December 2020

IL-22 increases the innate immunity of tissues

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12 December 2020

IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation

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12 December 2020

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)

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12 December 2020

Gene expression profiling in autoimmune noninfectious uveitis disease

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Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

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Cutting edge: immune cells as sources and targets of the IL-10 family members?

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12 December 2020

Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15

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12 December 2020

Potentiation of IL-19 expression in airway epithelia by IL-17A and IL-4/IL-13: important implications in asthma

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12 December 2020

Immunopathogenesis of psoriasis

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12 December 2020

Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway

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12 December 2020

IL-10 family of cytokines

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12 December 2020

IL-29 is produced by T(H)17 cells and mediates the cutaneous antiviral competence in psoriasis.

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12 December 2020

Anti-inflammatory cytokine interleukin-19 inhibits smooth muscle cell migration and activation of cytoskeletal regulators of VSMC motility

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12 December 2020

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

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12 December 2020

The murine liver is a potential target organ for IL-19, IL-20 and IL-24: Type I Interferons and LPS regulate the expression of IL-20R2

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12 December 2020

Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions

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12 December 2020

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses

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12 December 2020

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

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12 December 2020

Interleukin (IL)-19, IL-20 and IL-24 are produced by and act on keratinocytes and are distinct from classical ILs

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12 December 2020

Targeting IL-17 and TH17 cells in chronic inflammation

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12 December 2020

The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis

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12 December 2020

Therapeutic opportunities of the IL-22-IL-22R1 system

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12 December 2020

Interleukin-19 (IL-19) induces heme oxygenase-1 (HO-1) expression and decreases reactive oxygen species in human vascular smooth muscle cells.

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12 December 2020

Pathogenesis and clinical features of psoriasis

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12 December 2020

Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.

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12 December 2020

Expression of IL-19 and its receptors in RA: potential role for synovial hyperplasia formation.

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12 December 2020

The anti-inflammatory cytokine interleukin 19 is expressed by and angiogenic for human endothelial cells

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12 December 2020

Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)

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12 December 2020

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

1 reference

12 December 2020

Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor

1 reference

12 December 2020

The psoriasis-associated D10N variant of the adaptor Act1 with impaired regulation by the molecular chaperone hsp90.

1 reference

12 December 2020

Interleukin-26: an IL-10-related cytokine produced by Th17 cells

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12 December 2020

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

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12 December 2020

The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis

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12 December 2020

Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice

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12 December 2020

Further association analysis of chr 6q22-24 suggests a role of IL-20RA polymorphisms in psoriasis

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12 December 2020

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

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12 December 2020

Possible relations between the polymorphisms of the cytokines IL-19, IL-20 and IL-24 and plaque-type psoriasis

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12 December 2020

IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not.

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12 December 2020

The biological functions of T helper 17 cell effector cytokines in inflammation

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12 December 2020

Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model

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12 December 2020