Mitochondrial toxic effects of Aβ through mitofusins in the early pathogenesis of Alzheimer's disease. (Q53351303)

13 May 2018

http://europepmc.org/abstract/MED/24710686

title

Mitochondrial toxic effects of Aβ through mitofusins in the early pathogenesis of Alzheimer's disease. (English)

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13 May 2018

http://europepmc.org/abstract/MED/24710686

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1

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13 June 2020

author name string

Yushan Zhu

2

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13 June 2020

Xingshui Cao

3

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13 June 2020

Shufeng Sun

4

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13 June 2020

Baolu Zhao

5

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13 June 2020

publication date

8 April 2014

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13 May 2018

http://europepmc.org/abstract/MED/24710686

published in

Molecular Neurobiology

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13 June 2020

volume

50

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13 June 2020

issue

3

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13 June 2020

page(s)

986-996

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Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

13 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

The Alzheimer's disease mitochondrial cascade hypothesis: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondrial cascade hypothesis of Alzheimer's disease: myth or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Intracellular amyloid-beta in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Electron transport chain defects in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

β-Amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Gender differences in the amount and deposition of amyloidbeta in APPswe and PS1 double transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Sensorimotor gating and memory deficits in an APP/PS1 double transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

FLZ alleviates the memory deficits in transgenic mouse model of Alzheimer's disease via decreasing beta-amyloid production and tau hyperphosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Neurogenesis in the adult human hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Superoxide anion regulates the mitochondrial free Ca2+ through uncoupling proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

UCP2-dependent proton leak in isolated mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Superoxide stimulates a proton leak in potato mitochondria that is related to the activity of uncoupling protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

L-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced excitotoxicity via inhibition of the NMDA receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Neurogenesis and Alzheimer's disease: at the crossroads

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Biological markers of amyloid beta-related mechanisms in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

APP/PS1KI bigenic mice develop early synaptic deficits and hippocampus atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondrial fusion and fission in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Quantitative proteomic analysis of mitochondria in aging PS-1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

l-Theanine, an amino acid in green tea, attenuates beta-amyloid-induced cognitive dysfunction and neurotoxicity: reduction in oxidative damage and inactivation of ERK/p38 kinase and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Neuroprotective effects of theanine and its preventive effects on cognitive dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-8675-Z

Intra- and extracellular Abeta and PHF in clinically evaluated cases of Alzheimer's disease

21 January 2018

1 reference

12 December 2020

Nicotine attenuates beta-amyloid-induced neurotoxicity by regulating metal homeostasis

1 reference

12 December 2020

Alzheimer's APP mangles mitochondria

1 reference

12 December 2020

Pathogenesis of Alzheimer's disease

1 reference

12 December 2020

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

1 reference

12 December 2020

Mitochondrial abnormalities in Alzheimer's disease.

1 reference

12 December 2020