RhoB facilitates c-Myc turnover by supporting efficient nuclear accumulation of GSK-3. (Q53353124)

13 May 2018

title

RhoB facilitates c-Myc turnover by supporting efficient nuclear accumulation of GSK-3. (English)

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13 May 2018

author name string

M Huang

series ordinal

1

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13 May 2018

U Kamasani

series ordinal

2

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13 May 2018

G C Prendergast

series ordinal

3

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13 May 2018

language of work or name

English

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publication date

1 March 2006

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13 May 2018

published in

Oncogene

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13 May 2018

volume

25

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13 May 2018

issue

9

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13 May 2018

page(s)

1281-1289

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13 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209174

exact match

0 references

cites work

Intracellular localization of the P21rho proteins

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RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development

21 January 2018

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c-Jun-NH2 kinase (JNK) contributes to the regulation of c-Myc protein stability.

21 January 2018

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Regulation of c-myc stability by selective stress conditions and by MEKK1 requires aa 127-189 of c-myc.

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Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas

21 January 2018

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Cell growth inhibition by farnesyltransferase inhibitors is mediated by gain of geranylgeranylated RhoB.

21 January 2018

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Stimulus-dependent regulation of serum and glucocorticoid inducible protein kinase (SGK) transcription, subcellular localization and enzymatic activity

21 January 2018

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myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome

21 January 2018

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Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase

21 January 2018

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Regulation of epidermal growth factor receptor traffic by the small GTPase rhoB

21 January 2018

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Phosphorylation by Glycogen Synthase Kinase-3 Controls c-Myc Proteolysis and Subnuclear Localization

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Rho GTPases in transformation and metastasis.

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The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis

21 January 2018

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RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

21 January 2018

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RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitors

21 January 2018

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RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells

21 January 2018

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Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis

21 January 2018

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Loss of RhoB expression in human lung cancer progression.

21 January 2018

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PRK1 is targeted to endosomes by the small GTPase, RhoB

21 January 2018

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MYC oncogenes and human neoplastic disease

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Actin' up: RhoB in cancer and apoptosis

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Differing Roles of Akt and Serum- and Glucocorticoid-regulated Kinase in Glucose Metabolism, DNA Synthesis, and Oncogenic Activity

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Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.

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RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane

21 January 2018

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Ras enhances Myc protein stability.

21 January 2018

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Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

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New colorimetric cytotoxicity assay for anticancer-drug screening

21 January 2018

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Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

21 January 2018

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Histone deacetylase 1 represses the small GTPase RhoB expression in human nonsmall lung carcinoma cell line

21 January 2018

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The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase

21 January 2018

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A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

21 January 2018

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The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

21 January 2018

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Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase

21 January 2018

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Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

21 January 2018

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A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

21 January 2018

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Role for RhoB and PRK in the suppression of epithelial cell transformation by farnesyltransferase inhibitors

21 January 2018

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Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Geranylgeranylated RhoB is sufficient to mediate tissue-specific suppression of Akt kinase activity by farnesyltransferase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209174

inferred from DOI database lookup

7 January 2021

based on heuristic

Sequence curiosity in v-myc oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209174

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1209174

1 reference

13 May 2018

PubMed ID

16247449

1 reference

13 May 2018