Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype. (Q53379260)

13 May 2018

title

Increased ezrin expression and activation by CDK5 coincident with acquisition of the senescent phenotype. (English)

1 reference

13 May 2018

author name string

Hai-Su Yang

series ordinal

1

1 reference

13 May 2018

Philip W Hinds

series ordinal

2

1 reference

13 May 2018

publication date

1 May 2003

1 reference

13 May 2018

published in

Molecular Cell

1 reference

13 May 2018

volume

11

1 reference

13 May 2018

issue

5

1 reference

13 May 2018

page(s)

1163-1176

1 reference

13 May 2018

Requirement for p27(KIP1) in retinoblastoma protein-mediated senescence

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Regulation of cortical structure by the ezrin-radixin-moesin protein family

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Actin, its associated proteins and metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Replicative senescence: an old lives' tale?

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

p16 INK4a can initiate an autonomous senescence program

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Replicative senescence: the human fibroblast comes of age.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Essential functions of ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

ERM proteins: from cellular architecture to cell signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Genes involved in senescence and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Interdomain interactions of radixin in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

1 reference

7 January 2021

Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Identification of a growth suppression domain within the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Replicative senescence: implications for in vivo aging and tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Interaction of radixin with Rho small G protein GDP/GTP exchange protein Dbl

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Structure and regulation of the CDK5-p25(nck5a) complex

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Induction of DNA synthesis and apoptosis by regulated inactivation of a temperature-sensitive retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Rho activity can alter the translation of p27 mRNA and is important for RasV12-induced transformation in a manner dependent on p27 status.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

Signal transduction and actin filament organization

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900135-7

7 January 2021

10.1016/S1097-2765(03)00135-7

Identifiers

DOI

1 reference

13 May 2018

PubMed ID

12769842

1 reference

13 May 2018