Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver. (Q53381584)

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English	Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver.	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

Constitutively active mutant D816VKit induces megakayocyte and mast cell differentiation of early haemopoietic cells from murine foetal liver. (English)

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

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cell differentiation

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inferred from title

author name string

Petranel T Ferrao

1

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

Thomas J Gonda

2

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

Leonie K Ashman

3

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

publication date

1 June 2003

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

Leukemia Research

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

27

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

6

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

547-555

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

The biology of stem cell factor and its receptor C-kit

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Early signaling pathways activated by c-Kit in hematopoietic cells

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7 January 2021

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Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

1 reference

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Identification of activating c-kit mutations in adult-, but not in childhood-onset indolent mastocytosis: a possible explanation for divergent clinical behavior

1 reference

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Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm

1 reference

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7 January 2021

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Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis

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Mastocytosis cells bearing a c-kit activating point mutation are characterized by hypersensitivity to stem cell factor and increased apoptosis

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Detection of c-kit mutation Asp 816 to Val in microdissected bone marrow infiltrates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia.

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A case of 'smouldering' mastocytosis with high mast cell burden, monoclonal myeloid cells, and C-KIT mutation Asp-816-Val

1 reference

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7 January 2021

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Effects of mutant c-kit in early myeloid cells.

1 reference

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7 January 2021

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Activating mutations of c-kit at codon 816 confer drug resistance in human leukemia cells

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Activating c-kit gene mutations in human germ cell tumors

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Clinical correlates of the presence of the Asp816Val c-kit mutation in the peripheral blood mononuclear cells of patients with mastocytosis

1 reference

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Systemic mastocytosis associated with acute myeloid leukaemia: report of two cases and detection of the c-kit mutation Asp-816 to Val

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900272-2

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of the surface expression of c-kit and occurrence of the c-kit Asp816Val activating mutation in T cells, B cells, and myelomonocytic cells in patients with mastocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900272-2

7 January 2021

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Mutation analysis of C-KIT in patients with myelodysplastic syndromes without mastocytosis and cases of systemic mastocytosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900272-2

7 January 2021

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Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

1 reference

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7 January 2021

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Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

1 reference

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7 January 2021

based on heuristic

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Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900272-2

7 January 2021

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Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor

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Safety and efficacy of imatinib (STI571) in metastatic gastrointestinal stromal tumours: a phase I study

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900272-2

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The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900272-2

7 January 2021

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Substitution of an aspartic acid results in constitutive activation of c-kit receptor tyrosine kinase in a rat tumor mast cell line RBL-2H3

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900272-2

7 January 2021

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Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1

1 reference

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7 January 2021

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Phosphatidylinositol 3 kinase contributes to the transformation of hematopoietic cells by the D816V c-Kit mutant

1 reference

https://api.crossref.org/works/10.1016%2FS0145-2126%2802%2900272-2

7 January 2021

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Signal transducer and activator of transcription 3 activation is required for Asp(816) mutant c-Kit-mediated cytokine-independent survival and proliferation in human leukemia cells

1 reference

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A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES

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Interspecies molecular chimeras of kit help define the binding site of the stem cell factor

1 reference

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Primary structure and functional expression of rat and human stem cell factor DNAs

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Role of aspartic acid 814 in the function and expression of c-kit receptor tyrosine kinase

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Specificity of a mouse monoclonal antibody raised against acute myeloid leukaemia cells for mast cells in human mucosal and connective tissues.

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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

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High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

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Transformation of NIH3T3 fibroblasts by the c-Kit receptor tyrosine kinase: effect of receptor density and ligand-requirement

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Multilineage involvement and erythropoietin-"independent" erythroid progenitor cells in a patient with systemic mastocytosis

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Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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Identifiers

10.1016/S0145-2126(02)00272-2

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/12648515

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