Association of ERG and TMPRSS2-ERG with grade, stage, and prognosis of prostate cancer is dependent on their expression levels. (Q53519887)

http://europepmc.org/abstract/MED/25939480

15 May 2018

title

Association of ERG and TMPRSS2-ERG with grade, stage, and prognosis of prostate cancer is dependent on their expression levels. (English)

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http://europepmc.org/abstract/MED/25939480

15 May 2018

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1

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10 June 2020

José Antonio Lorente

5

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10 June 2020

Lluís Fumadó

6

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10 June 2020

author name string

Núria Juanpere

2

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10 June 2020

Silvia de Muga

3

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10 June 2020

Marta Lorenzo

4

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10 June 2020

Laia Serrano

7

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10 June 2020

Sergio Serrano

8

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10 June 2020

Josep Lloreta

9

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10 June 2020

Silvia Hernández

10

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10 June 2020

publication date

4 May 2015

1 reference

http://europepmc.org/abstract/MED/25939480

15 May 2018

published in

The Prostate

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10 June 2020

volume

75

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10 June 2020

issue

11

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10 June 2020

page(s)

1216-1226

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Role of the TMPRSS2-ERG gene fusion in prostate cancer

10 June 2020

cites work

1 reference

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The genomic complexity of primary human prostate cancer

21 January 2018

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Oncogenic activation of ERG: A predominant mechanism in prostate cancer

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Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements

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Nucleotide resolution analysis of TMPRSS2 and ERG rearrangements in prostate cancer

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TMPRSS2-ERG-mediated feed-forward regulation of wild-type ERG in human prostate cancers.

21 January 2018

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5' UTR control of native ERG and of Tmprss2:ERG variants activity in prostate cancer

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Recurrent gene fusions in prostate cancer

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Prognostic value of ERG oncoprotein in prostate cancer recurrence and cause-specific mortality

21 January 2018

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Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome

21 January 2018

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TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis.

21 January 2018

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ERG protein expression reflects hormonal treatment response and is associated with Gleason score and prostate cancer specific mortality

21 January 2018

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TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy

21 January 2018

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ERG immunohistochemistry is not predictive for PSA recurrence, local recurrence or overall survival after radical prostatectomy for prostate cancer

21 January 2018

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Complex patterns of ETS gene alteration arise during cancer development in the human prostate

21 January 2018

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Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression

21 January 2018

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Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

21 January 2018

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Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

21 January 2018

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Molecular alterations of EGFR and PTEN in prostate cancer: association with high-grade and advanced-stage carcinomas.

21 January 2018

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PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade

21 January 2018

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High-resolution ERG-expression profiling on GeneChip exon 1.0 ST arrays in primary and castration-resistant prostate cancer.

21 January 2018

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ERG overexpression and PTEN status predict capsular penetration in prostate carcinoma

21 January 2018

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An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

21 January 2018

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Androgen receptor and prostate cancer

21 January 2018

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Androgen receptor and gene network: Micromechanics reassemble the signaling machinery of TMPRSS2-ERG positive prostate cancer cells

21 January 2018

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Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

21 January 2018

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Antibody-based detection of ERG rearrangement-positive prostate cancer

21 January 2018

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Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas

21 January 2018

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Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays

21 January 2018

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TMPRSS2-ERG expression predicts prostate cancer survival and associates with stromal biomarkers

21 January 2018

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TMPRSS2:ERG gene fusion predicts subsequent detection of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia

21 January 2018

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TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features

21 January 2018

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A panel of TMPRSS2:ERG fusion transcript markers for urine-based prostate cancer detection with high specificity and sensitivity

21 January 2018

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Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer

21 January 2018

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A novel four-color fluorescence in situ hybridization assay for the detection of TMPRSS2 and ERG rearrangements in prostate cancer

21 January 2018

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ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy.

21 January 2018

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ERG expression in prostate cancer: the prognostic paradox

21 January 2018

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Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target?

21 January 2018

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TMPRSS2-ERG fusions are strongly linked to young patient age in low-grade prostate cancer.

21 January 2018

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Antibody EPR3864 is specific for ERG genomic fusions in prostate cancer: implications for pathological practice.

21 January 2018

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Quantitative analysis of ERG expression and its splice isoforms in formalin-fixed, paraffin-embedded prostate cancer samples: association with seminal vesicle invasion and biochemical recurrence.

21 January 2018

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Loss of PTEN expression is associated with increased risk of recurrence after prostatectomy for clinically localized prostate cancer

21 January 2018

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Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis.

21 January 2018

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TMPRSS2-ERG Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion

21 January 2018

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Genomic Deletion of PTEN Is Associated with Tumor Progression and Early PSA Recurrence in ERG Fusion-Positive and Fusion-Negative Prostate Cancer

21 January 2018

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Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome

21 January 2018

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A Comparative Study of ERG Status Assessment on DNA, mRNA, and Protein Levels Using Unique Samples from a Swedish Biopsy Cohort

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PROS.23004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25939480%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference