A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes. (Q53538448)

15 May 2018

title

A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes. (English)

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15 May 2018

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Tanja Arndt

1

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15 May 2018

Dirk Wedekind

2

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15 May 2018

Anne Jörns

3

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15 May 2018

Georgios Tsiavaliaris

4

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15 May 2018

Edwin Cuppen

5

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15 May 2018

Hans-Jürgen Hedrich

6

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15 May 2018

Sigurd Lenzen

7

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15 May 2018

publication date

12 September 2015

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15 May 2018

published in

Diabetologia

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15 May 2018

volume

58

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15 May 2018

page(s)

2800-2809

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15 May 2018

issue

12

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15 May 2018

https://scigraph.springernature.com/pub.10.1007/s00125-015-3757-7

exact match

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cites work

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The mutation of the LEW.1AR1-iddm rat maps to the telomeric end of rat chromosome 1.

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21 January 2018

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21 January 2018

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New Inbred Strain of Long-Evans Tokushima Lean Rats With IDDM Without Lymphopenia

21 January 2018

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12 December 2020

Cblb is a major susceptibility gene for rat type 1 diabetes mellitus

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A variable CD3⁺ T-cell frequency in peripheral blood lymphocytes associated with type 1 diabetes mellitus development in the LEW.1AR1-iddm rat.

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Immune cell infiltration, cytokine expression, and beta-cell apoptosis during the development of type 1 diabetes in the spontaneously diabetic LEW.1AR1/Ztm-iddm rat

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Anti-TCR therapy combined with fingolimod for reversal of diabetic hyperglycemia by β cell regeneration in the LEW.1AR1-iddm rat model of type 1 diabetes

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Genetic analysis of the LEW.1AR1-iddm rat: an animal model for spontaneous diabetes mellitus

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12 December 2020

Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

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12 December 2020

10.1007/S00125-015-3757-7

Identifiers

DOI

1 reference

15 May 2018

PubMed ID

26363782

1 reference

15 May 2018