Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat. (Q53573537)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

0 references

1 reference

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Wendy Keung

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Natasha Fillmore

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Sandra E Kelly

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Gary D Lopaschuk

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

John R Ussher

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

publication date

14 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

published in

Experimental Physiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

730-741

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

Skeletal muscle triglycerides, diacylglycerols, and ceramides in insulin resistance: another paradox in endurance-trained athletes?

3 March 2020

cites work

1 reference

MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats.

21 January 2018

1 reference

Potential mechanisms and consequences of cardiac triacylglycerol accumulation in insulin-resistant rats

21 January 2018

1 reference

Ceramides as modulators of cellular and whole-body metabolism

21 January 2018

1 reference

Plasma membrane subdomain compartmentalization contributes to distinct mechanisms of ceramide action on insulin signaling

21 January 2018

1 reference

Sphingolipid metabolism and analysis in metabolic disease

21 January 2018

1 reference

Animal models of insulin resistance and cardiovascular disease: some therapeutic approaches using JCR:LA-cp rat.

21 January 2018

1 reference

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

21 January 2018

1 reference

A ceramide-centric view of insulin resistance

21 January 2018

1 reference

Insulin resistance is associated with higher intramyocellular triglycerides in type I but not type II myocytes concomitant with higher ceramide content

21 January 2018

1 reference

Reduced skeletal muscle oxidative capacity and elevated ceramide but not diacylglycerol content in severe obesity

21 January 2018

1 reference

Characterization of fiber types in different muscles of the hindlimb in female weanling and adult Wistar rats

21 January 2018

1 reference

Pathogenesis of NIDDM. A balanced overview

21 January 2018

1 reference

Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats

21 January 2018

1 reference

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

21 January 2018

1 reference

Divergent role of sphingosine 1-phosphate on insulin resistance

21 January 2018

1 reference

Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake

21 January 2018

1 reference

Dietary supplementation of n-3 PUFA reduces weight gain and improves postprandial lipaemia and the associated inflammatory response in the obese JCR:LA-cp rat.

21 January 2018

1 reference

An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice

21 January 2018

1 reference

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice

21 January 2018

1 reference

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

21 January 2018

1 reference

Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle

21 January 2018

1 reference

Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

21 January 2018

1 reference

Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance.

21 January 2018

1 reference

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

21 January 2018

1 reference

Regulation of the pyruvate dehydrogenase complex

21 January 2018

1 reference

Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism.

21 January 2018

1 reference

Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells

21 January 2018

1 reference

Development of insulin resistance in the JCR:LA-cp rat: role of triacylglycerols and effects of MEDICA 16.

21 January 2018

1 reference

Lipid-induced insulin resistance: unravelling the mechanism

21 January 2018

1 reference

Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance

21 January 2018

1 reference

Insulin sensitivity: modulation by nutrients and inflammation

21 January 2018

1 reference

Fiber types in mammalian skeletal muscles

21 January 2018

1 reference

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

21 January 2018

1 reference

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

21 January 2018

1 reference

Fibre type composition of soleus and extensor digitorum longus muscles in normal female inbred Lewis rats

21 January 2018

1 reference

Ceramides in insulin resistance and lipotoxicity

21 January 2018

1 reference

Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection

21 January 2018

1 reference

Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance.

21 January 2018

1 reference

Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle.

21 January 2018

1 reference

Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption

21 January 2018

1 reference

Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase

21 January 2018

1 reference

Regulation of plasma ceramide levels with fatty acid oversupply: evidence that the liver detects and secretes de novo synthesised ceramide.

21 January 2018

1 reference

Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat.

21 January 2018

1 reference

"Fast" and "slow" muscle fibres in hindlimb muscles of adult rats regenerate from intrinsically different satellite cells

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1113/EP085052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25786668%20AND%20SRC:MED&resulttype=core&format=json

release_zonuvzt5t5dmdaqvn6ithlhole

3 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zonuvzt5t5dmdaqvn6ithlhole

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference